Lung Cancer Risk Among Cooks When Accounting for Tobacco Smoking: A Pooled Analysis of Case-Control Studies From Europe, Canada, New Zealand, and China

Carolina Bigert, Per Gustavsson, Kurt Straif, Beate Pesch, Thomas Brüning, Benjamin Kendzia, Joachim Schüz, Isabelle Stücker, Florence Guida, Irene Brüske, Heinz Erich Wichmann, Angela C. Pesatori, Maria Teresa Landi, Neil Caporaso, Lap Ah Tse, Ignatius Tak Sun Yu, Jack Siemiatycki, Javier Pintos, Franco Merletti, Dario MirabelliLorenzo Simonato, Karl Heinz Jöckel, Wolfgang Ahrens, Hermann Pohlabeln, Adonina Tardón, David Zaridze, John Field, Andrea 'T Mannetje, Neil Pearce, John McLaughlin, Paul Demers, Neonila Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Rodica Stanescu Dumitru, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paolo Boffetta, Francesco Forastiere, Bas Bueno-De-Mesquita, Susan Peters, Roel Vermeulen, Hans Kromhout, Ann C. Olsson

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVES: To investigate the risk of lung cancer among cooks, while controlling for smoking habits. METHODS: We used data from the SYNERGY project including pooled information on lifetime work histories and smoking habits from 16 case-control studies conducted in Europe, Canada, New Zealand, and China. RESULTS: Before adjustment for smoking, we observed an increased risk of lung cancer in male cooks, but not in female cooks. After adjusting, there was no increased risk and no significant exposure-response relationship. Nevertheless, subgroup analyses highlighted some possible excess risks of squamous cell carcinoma and small cell carcinoma in female cooks. CONCLUSIONS: There is evidence that lung cancer risks among cooks may be confounded by smoking. After adjustment, cooks did not experience an increased risk of lung cancer overall. The subgroup analyses showing some excess risks among female cooks require cautious interpretation.

Original languageEnglish
Pages (from-to)202-209
Number of pages8
JournalJournal of Occupational and Environmental Medicine
Volume57
Issue number2
DOIs
Publication statusPublished - Feb 13 2015

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Medicine(all)

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