Lung-deflating ability of rib cage and abdominal muscles in rabbits

Edgardo D'Angelo, Edi Prandi, Emanuela D'Angelo, Matteo Pecchiari

Research output: Contribution to journalArticle

Abstract

Anesthetized, apneic, mechanically ventilated rabbits were placed into a tilting plethysmograph that a rubber diaphragm, tightly fitting the animal's body just below the xiphoid process, separated into a rib cage and abdominal chamber. Expired volumes (ΔV) and abdominal pressure changes (ΔPab) were assessed in supine and upright posture during maximal rib cage (RCC) and/or abdominal compression (ABC) by pressurizing either or both chambers, and during maximal stimulations of abdominal muscles (ABS). With RCC, ΔV supine and upright amounted to 16±4.9 (mean±S.D.) and 20.9±7% of the vital capacity in supine posture (VCs) and to 75.8±14.5 and 44.8±13.9% of the expiratory reserve volume (ERV) in corresponding posture, ΔPab being negligible. With ABC, ΔV was 13.7±2 and 38.9±7.3% VCs and 68.4±14.8 and 84.4±10.5% ERV, respectively. Both ΔV and ΔPab were similar with ABC and ABS, independent of posture. If this applies also to RCC and expiratory rib cage muscle contraction, maximal expiratory effects of the latter (a) are larger in upright than supine posture; (b) contribute to ERV more in supine than upright posture; and (c) are similar to those caused by ABS in supine, but substantially smaller in upright posture.

Original languageEnglish
Pages (from-to)17-24
Number of pages8
JournalRespiratory Physiology and Neurobiology
Volume135
Issue number1
DOIs
Publication statusPublished - Apr 15 2003

Keywords

  • Mammals, rabbit
  • Mechanics of breathing, chest wall
  • Muscles, abdominal, thoracic
  • Posture, abdominal pressure
  • Pressure, abdominal, posture

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine
  • Neuroscience(all)

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