Lung function changes in older people with metabolic syndrome and diabetes

Simone Scarlata, Filippo Luca Fimognari, Matteo Cesari, Renato Giua, Alessandro Franco, Patrizio Pasqualetti, Ruggero Pastorelli, Raffaele Antonelli-Incalzi

Research output: Contribution to journalArticlepeer-review


Aim: Restrictive lung dysfunction (RLD; defined as reduced forced vital capacity [FVC] in the presence of normal forced expiratory volume in 1s [FEV1]/FVC ratio) is highly prevalent in the elderly, and is associated with diabetes, metabolic syndrome (MetS) and abdominal obesity. The aim of this study was to assess the relative contribution of diabetes, MetS and abdominal obesity in characterizing RLD in the elderly. Methods: This was cross-sectional analysis of 192 consecutive, community-dwelling persons (mean age 70.8±8 years). The participants were grouped according to the number of MetS components (i.e. 0, 1, 2, 3 or 4) and the presence of diabetes. According to the Adult Treatment Panel-III criteria, participants with three or four components were considered to be affected by MetS. Independent correlates of RLD and obstructive lung dysfunction (OLD; FEV1/FVC

Original languageEnglish
Pages (from-to)894-900
Number of pages7
JournalGeriatrics and Gerontology International
Issue number4
Publication statusPublished - Oct 2013


  • Insulin resistance
  • Metabolic syndrome
  • Obstructive lung dysfunction
  • Restrictive lung dysfunction
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Gerontology
  • Health(social science)


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