Lung nodule and functional changes in smokers after smoking cessation short-term treatment

Eliana Maci, Francesca Comito, Anna Maria Frezza, Giuseppe Tonini, Aldo Pezzuto

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Tobacco smoke causes lung disfunction and inflammation. Methods: Twenty-two consecutive smokers with undetermined lung nodules were included. All underwent a baseline imaging, exhaled carbon monoxide level evaluation and spirometry, repeated at three months from smoking cessation therapy. Results: A significant reduction in size of the lung nodules was reported (p = .037) as a trend in number reduction (p = .11). A significant increase in blood arterial oxygen pressure (p <.0001), heart rate reduction (p <.01), and FEV1 increase (p <.0001) was recorded. Conclusions: Smoking cessation reduces number and size of lung nodules and improves in lung functionality. Copyright

Original languageEnglish
Pages (from-to)388-393
Number of pages6
JournalCancer Investigation
Volume32
Issue number8
DOIs
Publication statusPublished - Sep 14 2014

Keywords

  • High resolution tomography
  • Lung nodule evolution
  • Smoking cessation
  • Tobacco

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

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