Lung ultrasound features of children with complicated and noncomplicated community acquired pneumonia: A prospective study

Anna Maria Musolino, Paolo Tomà, Maria Chiara Supino, Barbara Scialanga, Alessia Mesturino, Simona Scateni, Massimo Battaglia, Nicola Pirozzi, Caterina Bock, Danilo Buonsenso

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: The purpose of this study was to describe lung ultrasound (LUS) findings at baseline and 48 hours after the beginning of treatment and evaluate how they correlate with outcome DESIGN: We prospectively analyzed patients from 1 month to 17 years of age with community acquired pneumonia (CAP) evaluated at a tertiary level pediatric hospital. At baseline and 48 hours after the beginning of treatment, history, clinical examination, laboratory testing, chest X-ray, and LUS were performed.

RESULTS: One hundred one children were enrolled in the study (13 with complicated CAP). At baseline those who developed complications presented a larger size of the subpleural pulmonary parenchymal lesions (P = .001) often associated with a complex pleural effusion (63.6%, P = .013). Those with an uncomplicated CAP presented an air, arboriform, superficial and dynamic bronchogram, as opposed to complicated CAP which had an air and liquid bronchogram, deep, fixed (P = .001). At the 48-hour control in the noncomplicated CAP group, bronchogram was more frequently superficial and dynamic (P = .050). Pleural effusion disappeared in half cases (P = .050). In all patients, neutrophilic leucocytosis with increased C-reactive protein was detected and decreased at control (P = .001). The linear regression analyses showed the switch from a deep to a superficial bronchogram as the only explanatory variable (r = 0.97, R2  = 0.94, P = .001, t = 10.73).

CONCLUSIONS: Our study describe early LUS features of CAP that might be able to predict the development of complicated CAP.

Original languageEnglish
JournalPediatric Pulmonology
DOIs
Publication statusE-pub ahead of print - Jul 1 2019

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Pneumonia
Prospective Studies
Lung
Pleural Effusion
Air
Pediatric Hospitals
Leukocytosis
C-Reactive Protein
Linear Models
Thorax
History
Regression Analysis
X-Rays
Therapeutics

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Lung ultrasound features of children with complicated and noncomplicated community acquired pneumonia : A prospective study. / Musolino, Anna Maria; Tomà, Paolo; Supino, Maria Chiara; Scialanga, Barbara; Mesturino, Alessia; Scateni, Simona; Battaglia, Massimo; Pirozzi, Nicola; Bock, Caterina; Buonsenso, Danilo.

In: Pediatric Pulmonology, 01.07.2019.

Research output: Contribution to journalArticle

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abstract = "OBJECTIVE: The purpose of this study was to describe lung ultrasound (LUS) findings at baseline and 48 hours after the beginning of treatment and evaluate how they correlate with outcome DESIGN: We prospectively analyzed patients from 1 month to 17 years of age with community acquired pneumonia (CAP) evaluated at a tertiary level pediatric hospital. At baseline and 48 hours after the beginning of treatment, history, clinical examination, laboratory testing, chest X-ray, and LUS were performed.RESULTS: One hundred one children were enrolled in the study (13 with complicated CAP). At baseline those who developed complications presented a larger size of the subpleural pulmonary parenchymal lesions (P = .001) often associated with a complex pleural effusion (63.6{\%}, P = .013). Those with an uncomplicated CAP presented an air, arboriform, superficial and dynamic bronchogram, as opposed to complicated CAP which had an air and liquid bronchogram, deep, fixed (P = .001). At the 48-hour control in the noncomplicated CAP group, bronchogram was more frequently superficial and dynamic (P = .050). Pleural effusion disappeared in half cases (P = .050). In all patients, neutrophilic leucocytosis with increased C-reactive protein was detected and decreased at control (P = .001). The linear regression analyses showed the switch from a deep to a superficial bronchogram as the only explanatory variable (r = 0.97, R2  = 0.94, P = .001, t = 10.73).CONCLUSIONS: Our study describe early LUS features of CAP that might be able to predict the development of complicated CAP.",
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T1 - Lung ultrasound features of children with complicated and noncomplicated community acquired pneumonia

T2 - A prospective study

AU - Musolino, Anna Maria

AU - Tomà, Paolo

AU - Supino, Maria Chiara

AU - Scialanga, Barbara

AU - Mesturino, Alessia

AU - Scateni, Simona

AU - Battaglia, Massimo

AU - Pirozzi, Nicola

AU - Bock, Caterina

AU - Buonsenso, Danilo

N1 - © 2019 Wiley Periodicals, Inc.

PY - 2019/7/1

Y1 - 2019/7/1

N2 - OBJECTIVE: The purpose of this study was to describe lung ultrasound (LUS) findings at baseline and 48 hours after the beginning of treatment and evaluate how they correlate with outcome DESIGN: We prospectively analyzed patients from 1 month to 17 years of age with community acquired pneumonia (CAP) evaluated at a tertiary level pediatric hospital. At baseline and 48 hours after the beginning of treatment, history, clinical examination, laboratory testing, chest X-ray, and LUS were performed.RESULTS: One hundred one children were enrolled in the study (13 with complicated CAP). At baseline those who developed complications presented a larger size of the subpleural pulmonary parenchymal lesions (P = .001) often associated with a complex pleural effusion (63.6%, P = .013). Those with an uncomplicated CAP presented an air, arboriform, superficial and dynamic bronchogram, as opposed to complicated CAP which had an air and liquid bronchogram, deep, fixed (P = .001). At the 48-hour control in the noncomplicated CAP group, bronchogram was more frequently superficial and dynamic (P = .050). Pleural effusion disappeared in half cases (P = .050). In all patients, neutrophilic leucocytosis with increased C-reactive protein was detected and decreased at control (P = .001). The linear regression analyses showed the switch from a deep to a superficial bronchogram as the only explanatory variable (r = 0.97, R2  = 0.94, P = .001, t = 10.73).CONCLUSIONS: Our study describe early LUS features of CAP that might be able to predict the development of complicated CAP.

AB - OBJECTIVE: The purpose of this study was to describe lung ultrasound (LUS) findings at baseline and 48 hours after the beginning of treatment and evaluate how they correlate with outcome DESIGN: We prospectively analyzed patients from 1 month to 17 years of age with community acquired pneumonia (CAP) evaluated at a tertiary level pediatric hospital. At baseline and 48 hours after the beginning of treatment, history, clinical examination, laboratory testing, chest X-ray, and LUS were performed.RESULTS: One hundred one children were enrolled in the study (13 with complicated CAP). At baseline those who developed complications presented a larger size of the subpleural pulmonary parenchymal lesions (P = .001) often associated with a complex pleural effusion (63.6%, P = .013). Those with an uncomplicated CAP presented an air, arboriform, superficial and dynamic bronchogram, as opposed to complicated CAP which had an air and liquid bronchogram, deep, fixed (P = .001). At the 48-hour control in the noncomplicated CAP group, bronchogram was more frequently superficial and dynamic (P = .050). Pleural effusion disappeared in half cases (P = .050). In all patients, neutrophilic leucocytosis with increased C-reactive protein was detected and decreased at control (P = .001). The linear regression analyses showed the switch from a deep to a superficial bronchogram as the only explanatory variable (r = 0.97, R2  = 0.94, P = .001, t = 10.73).CONCLUSIONS: Our study describe early LUS features of CAP that might be able to predict the development of complicated CAP.

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