Lung Ultrasound May Support Diagnosis and Monitoring of COVID-19 Pneumonia

Marco Allinovi, Alberto Parise, Martina Giacalone, Andrea Amerio, Marco Delsante, Anna Odone, Andrea Franci, Fabrizio Gigliotti, Silvia Amadasi, Davide Delmonte, Niccolò Parri, Angelo Mangia

Research output: Contribution to journalReview articlepeer-review


Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) is characterized by severe pneumonia and/or acute respiratory distress syndrome in about 20% of infected patients. Computed tomography (CT) is the routine imaging technique for diagnosis and monitoring of COVID-19 pneumonia. Chest CT has high sensitivity for diagnosis of COVID-19, but is not universally available, requires an infected or unstable patient to be moved to the radiology unit with potential exposure of several people, necessitates proper sanification of the CT room after use and is underutilized in children and pregnant women because of concerns over radiation exposure. The increasing frequency of confirmed COVID-19 cases is striking, and new sensitive diagnostic tools are needed to guide clinical practice. Lung ultrasound (LUS) is an emerging non-invasive bedside technique that is used to diagnose interstitial lung syndrome through evaluation and quantitation of the number of B-lines, pleural irregularities and nodules or consolidations. In patients with COVID-19 pneumonia, LUS reveals a typical pattern of diffuse interstitial lung syndrome, characterized by multiple or confluent bilateral B-lines with spared areas, thickening of the pleural line with pleural line irregularity and peripheral consolidations. LUS has been found to be a promising tool for the diagnosis of COVID-19 pneumonia, and LUS findings correlate fairly with those of chest CT scan. Compared with CT, LUS has several other advantages, such as lack of exposure to radiation, bedside repeatability during follow-up, low cost and easier application in low-resource settings. Consequently, LUS may decrease utilization of conventional diagnostic imaging resources (CT scan and chest X-ray). LUS may help in early diagnosis, therapeutic decisions and follow-up monitoring of COVID-19 pneumonia, particularly in the critical care setting and in pregnant women, children and patients in areas with high rates of community transmission.

Original languageEnglish
Pages (from-to)2908-2917
Number of pages10
JournalUltrasound in Medicine and Biology
Issue number11
Publication statusPublished - Nov 2020


  • Acute respiratory disease syndrome
  • B-Lines
  • COVID-19
  • Interstitial syndrome
  • Lung ultrasound
  • Pneumonia

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics


Dive into the research topics of 'Lung Ultrasound May Support Diagnosis and Monitoring of COVID-19 Pneumonia'. Together they form a unique fingerprint.

Cite this