Lymph node dissection during radical cystectomy for bladder cancer treatment: Considerations on relevance and extent

Lars Weisbach, Roland Dahlem, Giuseppe Simone, Jens Hansen, Armin Soave, Oliver Engel, Felix K. Chun, Shahrokh F. Shariat, Margit Fisch, Michael Rink

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Despite advances in the surgical and medical treatment for urothelial carcinoma of the bladder (UCB), there have only been limited improvements in disease-specific mortality rates over the past decades. Lymph node dissection (LND) during radical cystectomy is an integral part of the treatment for muscle-invasive and high-risk UCB. LND may detect and remove lymph node (LN) metastasis and thus guide patient counseling and decision making regarding additional treatment decisions. In addition, LND may improve survival in patients both with and without LN metastasis. In this non-systematic review article, we discuss benefits and risks of LND, the role of limited versus extended LND and the dilemma of preoperative LN staging.

Original languageEnglish
Pages (from-to)1561-1567
Number of pages7
JournalInternational Urology and Nephrology
Volume45
Issue number6
DOIs
Publication statusPublished - Dec 2013

Fingerprint

Cystectomy
Lymph Node Excision
Urinary Bladder Neoplasms
Lymph Nodes
Urinary Bladder
Neoplasm Metastasis
Carcinoma
Therapeutics
Counseling
Decision Making
Muscles
Survival
Mortality

Keywords

  • Bladder cancer
  • Lymphadenectomy
  • Prognosis
  • Prognostic models
  • Survival
  • Urothelial carcinoma

ASJC Scopus subject areas

  • Nephrology
  • Urology

Cite this

Lymph node dissection during radical cystectomy for bladder cancer treatment : Considerations on relevance and extent. / Weisbach, Lars; Dahlem, Roland; Simone, Giuseppe; Hansen, Jens; Soave, Armin; Engel, Oliver; Chun, Felix K.; Shariat, Shahrokh F.; Fisch, Margit; Rink, Michael.

In: International Urology and Nephrology, Vol. 45, No. 6, 12.2013, p. 1561-1567.

Research output: Contribution to journalArticle

Weisbach, L, Dahlem, R, Simone, G, Hansen, J, Soave, A, Engel, O, Chun, FK, Shariat, SF, Fisch, M & Rink, M 2013, 'Lymph node dissection during radical cystectomy for bladder cancer treatment: Considerations on relevance and extent', International Urology and Nephrology, vol. 45, no. 6, pp. 1561-1567. https://doi.org/10.1007/s11255-013-0503-2
Weisbach, Lars ; Dahlem, Roland ; Simone, Giuseppe ; Hansen, Jens ; Soave, Armin ; Engel, Oliver ; Chun, Felix K. ; Shariat, Shahrokh F. ; Fisch, Margit ; Rink, Michael. / Lymph node dissection during radical cystectomy for bladder cancer treatment : Considerations on relevance and extent. In: International Urology and Nephrology. 2013 ; Vol. 45, No. 6. pp. 1561-1567.
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