TY - JOUR
T1 - Lymph node metastases in malignant tumors of the paranasal sinuses
T2 - Prognostic value and treatment
AU - Cantù, Giulio
AU - Bimbi, Gabriella
AU - Miceli, Rosalba
AU - Mariani, Luigi
AU - Colombo, Sarah
AU - Riccio, Stefano
AU - Squadrelli, Massimo
AU - Battisti, Andrea
AU - Pompilio, Madia
AU - Rossi, Marco
PY - 2008/2
Y1 - 2008/2
N2 - Objective: To assess the frequency of nodal involvement and its prognostic value in malignant tumors of the paranasal sinuses, particularly in maxillary sinus squamous cell carcinoma. Design: Retrospective review. Setting: Tertiary cancer center. Patients: The medical records of 704 consecutive patients surgically treated for malignant tumors of the paranasal sinuses from January 1968 to March 2003 were reviewed. The tumors were staged according to American Joint Committee on Cancer-International Union Against Cancer 2002 classification. Only patients with clinically positive nodes underwent a neck dissection. Main Outcome Measures: Lymph node metastases (at presentation or during follow-up, occurring alone, or with concurrent local recurrence and/or distant metastasis). Also analyzed were local recurrence (occurring alone or with concurrent distant metastasis), distant metastasis (occurring alone), and overall survival. Results: The tumor site was the ethmoid sinus in 305 cases and maxillary sinus in 399 cases. At baseline, 5 patients (1.6%) in the ethmoid sinus group and 33 (8.3%) in the maxillary sinus group presented with positive nodes (P
AB - Objective: To assess the frequency of nodal involvement and its prognostic value in malignant tumors of the paranasal sinuses, particularly in maxillary sinus squamous cell carcinoma. Design: Retrospective review. Setting: Tertiary cancer center. Patients: The medical records of 704 consecutive patients surgically treated for malignant tumors of the paranasal sinuses from January 1968 to March 2003 were reviewed. The tumors were staged according to American Joint Committee on Cancer-International Union Against Cancer 2002 classification. Only patients with clinically positive nodes underwent a neck dissection. Main Outcome Measures: Lymph node metastases (at presentation or during follow-up, occurring alone, or with concurrent local recurrence and/or distant metastasis). Also analyzed were local recurrence (occurring alone or with concurrent distant metastasis), distant metastasis (occurring alone), and overall survival. Results: The tumor site was the ethmoid sinus in 305 cases and maxillary sinus in 399 cases. At baseline, 5 patients (1.6%) in the ethmoid sinus group and 33 (8.3%) in the maxillary sinus group presented with positive nodes (P
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U2 - 10.1001/archoto.2007.30
DO - 10.1001/archoto.2007.30
M3 - Article
C2 - 18283160
AN - SCOPUS:39649091164
VL - 134
SP - 170
EP - 177
JO - Archives of otolaryngology (Chicago, Ill. : 1960)
JF - Archives of otolaryngology (Chicago, Ill. : 1960)
SN - 0003-9977
IS - 2
ER -