Lymphangiography in patients with ovarian epithelial cancer. An evaluation of 289 consecutive cases

R. Musumeci, A. Banfi, G. Bolis, G. B. Candiani, G. De Palo, F. Di Re, L. Lucina, A. Lattuada, C. Mangioni, G. Mattioli, N. Natale

Research output: Contribution to journalArticlepeer-review

Abstract

From January, 1973, to June, 1976, 226 patients with palpable ovarian masses were evaluated preoperatively by lymphography. Histology showed 166 cases of malignant epithelial tumors, 26 benign tumors, and 34 malignant special tumors (not included in this report). Furthermore, the group of patients included 99 recurrences of ovarian epithelial cancer and 24 patients who underwent restaging diagnostic procedures without clinical evidence of disease. Lymphography was negative in all patients with benign tumors. In the 289 cases of epithelial cancer, lymphangiography gave evidence of nodal metastases in 88 (30%). When the histological subtype was considered, the highest incidence of metastases was in undifferentiated carcinoma (50%) and the lowest, in mesonephroid carcinoma (14%). According to the stage before lymphography, nodal metastases were found in 8% of Stage I, 0% of Stage II, 29% of Stage III, and 53% of Stage IV cases. The incidence of metastases was 46% in patients studied for recurrent disease and 17% in patients studied for restaging. 54% of patients had metastases only in the pelvic nodes and 18% only in the para-aortic chains; in 28% both chains were involved simultaneously. Bilateral involvement was found in 63% of the positive cases. Retroperitoneal node biopsies were performed in 68 patients (36%). The radiologic/histologic correlation was 100% in the lymphangiographically positive cases; 81% in the negative cases, with 9 false-negative reports; and 87% in all cases.

Original languageEnglish
Pages (from-to)1444-1449
Number of pages6
JournalCancer
Volume40
Issue number4
Publication statusPublished - 1977

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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