DIE LYMPHOBLASTISCHE LYMPHOME DES KINDESALTERS. IHRE ERKENNBARKEIT ALS T- ODER B-ZELLNEOPLASIEN IM HISTOLOGISCHEN PRAPARAT (ROUTINE-SCHNITTPRAPARAT)

Translated title of the contribution: Lymphoblastic lymphomas in children. Their recognizability as T- or B-cell neoplasms in histologic slides (routine sections)

E. W. Schwarze, S. Pileri, G. Tolksdorf, J. Kampert-Blumberg

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Sections of lymph node and tumor biopsies from 60 patients (51 children, 9 adults) with lymphoblastic lymphoma (lbL) were examined in a blind trial to determine whether the subtype of lbL can be diagnosed on the basis of morphologic criteria alone. The diagnoses made in this trial were correct in 18 of 20 cases (adults and children) that had been classified as T-, B-, or non-T/non-B-lbL by immunologic, cytochemical (DAP IV), or virologic (EBV) analysis. In 48 of the 51 children, the subclassification made in the blind trial agreed with the definitive diagnosis. In addition to the results of the blind trial, the morphologic characteristics of T- and B-lbL are presented and the diagnostic value of cytochemical staining for acid phosphatases is discussed.

Original languageGerman
Pages (from-to)131-136
Number of pages6
JournalKlinische Padiatrie
Volume193
Issue number3
Publication statusPublished - 1981

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Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-Lymphocytes
Neoplasms
Acid Phosphatase
Human Herpesvirus 4
Lymph Nodes
Staining and Labeling
Biopsy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

DIE LYMPHOBLASTISCHE LYMPHOME DES KINDESALTERS. IHRE ERKENNBARKEIT ALS T- ODER B-ZELLNEOPLASIEN IM HISTOLOGISCHEN PRAPARAT (ROUTINE-SCHNITTPRAPARAT). / Schwarze, E. W.; Pileri, S.; Tolksdorf, G.; Kampert-Blumberg, J.

In: Klinische Padiatrie, Vol. 193, No. 3, 1981, p. 131-136.

Research output: Contribution to journalArticle

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abstract = "Sections of lymph node and tumor biopsies from 60 patients (51 children, 9 adults) with lymphoblastic lymphoma (lbL) were examined in a blind trial to determine whether the subtype of lbL can be diagnosed on the basis of morphologic criteria alone. The diagnoses made in this trial were correct in 18 of 20 cases (adults and children) that had been classified as T-, B-, or non-T/non-B-lbL by immunologic, cytochemical (DAP IV), or virologic (EBV) analysis. In 48 of the 51 children, the subclassification made in the blind trial agreed with the definitive diagnosis. In addition to the results of the blind trial, the morphologic characteristics of T- and B-lbL are presented and the diagnostic value of cytochemical staining for acid phosphatases is discussed.",
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AB - Sections of lymph node and tumor biopsies from 60 patients (51 children, 9 adults) with lymphoblastic lymphoma (lbL) were examined in a blind trial to determine whether the subtype of lbL can be diagnosed on the basis of morphologic criteria alone. The diagnoses made in this trial were correct in 18 of 20 cases (adults and children) that had been classified as T-, B-, or non-T/non-B-lbL by immunologic, cytochemical (DAP IV), or virologic (EBV) analysis. In 48 of the 51 children, the subclassification made in the blind trial agreed with the definitive diagnosis. In addition to the results of the blind trial, the morphologic characteristics of T- and B-lbL are presented and the diagnostic value of cytochemical staining for acid phosphatases is discussed.

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