Lymphocyte subpopulations in cerebro-spinal fluid of pediatric Guillain-Barre syndrome

In an attempt to characterize lymphocyte subpopulations of cerebrospinal fluid (CSF) in pediatric Guillain-Barre Syndrome (GBS), the authors studied surface markers of T and B cells in three children affected by this disease. Abnormal findings were detected in two cases in the acute phase of the disease. These findings consisted of a marked decrease of T and Tγ populations and of a relative increase of null-cells. The case studied in clinical remission following steroid therapy had normal lymphocyte subpopulations.