Lymphohistiocytic t-cell lymphoma and peripheral t-cell lymphoma associated with haemophagocytic syndrome: Two recently recognized entities which mimic malignant histiocytosis

Stefano Pileri, Elena Sabattini, Brunangelo Falini

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The lymphohistiocytic T-cell lymphoma and peripheral T-cell lymphoma associated with haemophagocytic syndrome are two distinct clinicopathologic entities which have recently been described. Due to the high content of reactive histiocytes, they share similar problems in the differential diagnosis with several reactive and neoplastic conditions. The criteria for the recognition of these tumours, along with the mechanisms which might attract the macrophagic component, are reviewed and extensively discussed.

Original languageEnglish
Pages (from-to)317-324
Number of pages8
JournalLeukemia and Lymphoma
Volume6
Issue number4-5
DOIs
Publication statusPublished - 1992

Fingerprint

Histiocytic Sarcoma
Peripheral T-Cell Lymphoma
Hemophagocytic Lymphohistiocytosis
Histiocytes
T-Cell Lymphoma
Lymphoma
Differential Diagnosis
Neoplasms

Keywords

  • Cytokine
  • Haemophagocytosis
  • Immunohistochemistry
  • Malignant histiocytosis
  • Molecular biology
  • Reactive histiocytosis
  • T-cell lymphoma

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

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AU - Sabattini, Elena

AU - Falini, Brunangelo

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AB - The lymphohistiocytic T-cell lymphoma and peripheral T-cell lymphoma associated with haemophagocytic syndrome are two distinct clinicopathologic entities which have recently been described. Due to the high content of reactive histiocytes, they share similar problems in the differential diagnosis with several reactive and neoplastic conditions. The criteria for the recognition of these tumours, along with the mechanisms which might attract the macrophagic component, are reviewed and extensively discussed.

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