Lymphoscintigraphy and radioguided biopsy of the sentinel axillary node in breast cancer

Concetta De Cicco, Marta Cremonesi, Alberto Luini, Mirco Bartolomei, Chiara Grana, Gennaro Prisco, Viviana Galimberti, Paolo Calza, Giuseppe Viale, Umberto Veronesi, Giovanni Paganelli

Research output: Contribution to journalArticlepeer-review


Lymphoscintigraphy associated with radioguided biopsy of the sentinel node (SN) is well established in clinical practice for melanoma. In breast cancer, the SN concept is similarly valid, and lymphoscintigraphy is a useful method for localizing the axillary SN. The aim of this study was to optimize the lymphoscintigraphy technique in association with a gamma ray detecting probe (GDP) for identifying and removing the SN in breast cancer patients. Methods: Two-hundred fifty patients with operable breast tumor underwent lymphoscintigraphy before surgery. Three different size ranges of 99mTc- labeled colloid particles (

Original languageEnglish
Pages (from-to)2080-2084
Number of pages5
JournalJournal of Nuclear Medicine
Issue number12
Publication statusPublished - Dec 1998


  • Breast cancer
  • Gamma ray detecting probe
  • Lymphoscintigraphy
  • Sentinel node

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology


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