Macronutrients, energy intake, and breast cancer risk: Implications from different models

Adriano Decarli, Adriano Favero, Carlo La Vecchia, Antonio Russo, Monica Ferraroni, Eva Negri, Silvia Franceschi

Research output: Contribution to journalArticle

Abstract

We used data from a case-control study, conducted in Italy on 2,569 incident cases of breast cancer and 2,588 controls, to fit various energy adjustment models in the estimate of the effect of selected nutrients and alcohol on breast cancer risk. When we fit the standard multivariate and residual models, including total energy intake and the different macronutrients one at a time, the odds ratios (OR) related to 100 kcal per day were 0.90 for protein, 0.96 for saturated fat, 0.88 for unsaturated fat, 0.95 for sugar, 1.07 for starch, and 1.06 for alcohol. When we included all of the different sources of calorie intake in a single model with energy sources partitioned, the OR of adding 100 kcal per day was 0.91 for protein, 1.22 for saturated fat, 0.89 for unsaturated fat, 0.98 for sugar, 1.08 for starch, and 1.07 for alcohol. The estimates from the residual models that included various macronutrients separately were similar to those of the extended energy partition model.

Original languageEnglish
Pages (from-to)425-428
Number of pages4
JournalEpidemiology
Volume8
Issue number4
DOIs
Publication statusPublished - Jul 1997

Fingerprint

Energy Intake
Unsaturated Fats
Alcohols
Breast Neoplasms
Starch
Fats
Odds Ratio
Italy
Case-Control Studies
Proteins
Food

Keywords

  • Breast neoplasms
  • Caloric intake
  • Diet
  • Dietary carbohydrates
  • Dietary fats
  • Dietary protein
  • Dietary sugar
  • Epidemiologic methods

ASJC Scopus subject areas

  • Epidemiology

Cite this

Decarli, A., Favero, A., La Vecchia, C., Russo, A., Ferraroni, M., Negri, E., & Franceschi, S. (1997). Macronutrients, energy intake, and breast cancer risk: Implications from different models. Epidemiology, 8(4), 425-428. https://doi.org/10.1097/00001648-199707000-00013

Macronutrients, energy intake, and breast cancer risk : Implications from different models. / Decarli, Adriano; Favero, Adriano; La Vecchia, Carlo; Russo, Antonio; Ferraroni, Monica; Negri, Eva; Franceschi, Silvia.

In: Epidemiology, Vol. 8, No. 4, 07.1997, p. 425-428.

Research output: Contribution to journalArticle

Decarli, A, Favero, A, La Vecchia, C, Russo, A, Ferraroni, M, Negri, E & Franceschi, S 1997, 'Macronutrients, energy intake, and breast cancer risk: Implications from different models', Epidemiology, vol. 8, no. 4, pp. 425-428. https://doi.org/10.1097/00001648-199707000-00013
Decarli, Adriano ; Favero, Adriano ; La Vecchia, Carlo ; Russo, Antonio ; Ferraroni, Monica ; Negri, Eva ; Franceschi, Silvia. / Macronutrients, energy intake, and breast cancer risk : Implications from different models. In: Epidemiology. 1997 ; Vol. 8, No. 4. pp. 425-428.
@article{24e8c1f00b544b2aa2f1806b7bee84a9,
title = "Macronutrients, energy intake, and breast cancer risk: Implications from different models",
abstract = "We used data from a case-control study, conducted in Italy on 2,569 incident cases of breast cancer and 2,588 controls, to fit various energy adjustment models in the estimate of the effect of selected nutrients and alcohol on breast cancer risk. When we fit the standard multivariate and residual models, including total energy intake and the different macronutrients one at a time, the odds ratios (OR) related to 100 kcal per day were 0.90 for protein, 0.96 for saturated fat, 0.88 for unsaturated fat, 0.95 for sugar, 1.07 for starch, and 1.06 for alcohol. When we included all of the different sources of calorie intake in a single model with energy sources partitioned, the OR of adding 100 kcal per day was 0.91 for protein, 1.22 for saturated fat, 0.89 for unsaturated fat, 0.98 for sugar, 1.08 for starch, and 1.07 for alcohol. The estimates from the residual models that included various macronutrients separately were similar to those of the extended energy partition model.",
keywords = "Breast neoplasms, Caloric intake, Diet, Dietary carbohydrates, Dietary fats, Dietary protein, Dietary sugar, Epidemiologic methods",
author = "Adriano Decarli and Adriano Favero and {La Vecchia}, Carlo and Antonio Russo and Monica Ferraroni and Eva Negri and Silvia Franceschi",
year = "1997",
month = "7",
doi = "10.1097/00001648-199707000-00013",
language = "English",
volume = "8",
pages = "425--428",
journal = "Epidemiology",
issn = "1044-3983",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Macronutrients, energy intake, and breast cancer risk

T2 - Implications from different models

AU - Decarli, Adriano

AU - Favero, Adriano

AU - La Vecchia, Carlo

AU - Russo, Antonio

AU - Ferraroni, Monica

AU - Negri, Eva

AU - Franceschi, Silvia

PY - 1997/7

Y1 - 1997/7

N2 - We used data from a case-control study, conducted in Italy on 2,569 incident cases of breast cancer and 2,588 controls, to fit various energy adjustment models in the estimate of the effect of selected nutrients and alcohol on breast cancer risk. When we fit the standard multivariate and residual models, including total energy intake and the different macronutrients one at a time, the odds ratios (OR) related to 100 kcal per day were 0.90 for protein, 0.96 for saturated fat, 0.88 for unsaturated fat, 0.95 for sugar, 1.07 for starch, and 1.06 for alcohol. When we included all of the different sources of calorie intake in a single model with energy sources partitioned, the OR of adding 100 kcal per day was 0.91 for protein, 1.22 for saturated fat, 0.89 for unsaturated fat, 0.98 for sugar, 1.08 for starch, and 1.07 for alcohol. The estimates from the residual models that included various macronutrients separately were similar to those of the extended energy partition model.

AB - We used data from a case-control study, conducted in Italy on 2,569 incident cases of breast cancer and 2,588 controls, to fit various energy adjustment models in the estimate of the effect of selected nutrients and alcohol on breast cancer risk. When we fit the standard multivariate and residual models, including total energy intake and the different macronutrients one at a time, the odds ratios (OR) related to 100 kcal per day were 0.90 for protein, 0.96 for saturated fat, 0.88 for unsaturated fat, 0.95 for sugar, 1.07 for starch, and 1.06 for alcohol. When we included all of the different sources of calorie intake in a single model with energy sources partitioned, the OR of adding 100 kcal per day was 0.91 for protein, 1.22 for saturated fat, 0.89 for unsaturated fat, 0.98 for sugar, 1.08 for starch, and 1.07 for alcohol. The estimates from the residual models that included various macronutrients separately were similar to those of the extended energy partition model.

KW - Breast neoplasms

KW - Caloric intake

KW - Diet

KW - Dietary carbohydrates

KW - Dietary fats

KW - Dietary protein

KW - Dietary sugar

KW - Epidemiologic methods

UR - http://www.scopus.com/inward/record.url?scp=0030905655&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030905655&partnerID=8YFLogxK

U2 - 10.1097/00001648-199707000-00013

DO - 10.1097/00001648-199707000-00013

M3 - Article

C2 - 9209858

AN - SCOPUS:0030905655

VL - 8

SP - 425

EP - 428

JO - Epidemiology

JF - Epidemiology

SN - 1044-3983

IS - 4

ER -