Macrophages and Metabolism in the Tumor Microenvironment

Ilio Vitale, Gwenola Manic, Lisa M. Coussens, Guido Kroemer, Lorenzo Galluzzi

Research output: Contribution to journalReview article

Abstract

Vitale et al. discuss the metabolic circuitries whereby tumor-associated macrophages condition their microenvironment to support the cancer growth, metastatic dissemination and resistance to treatment, and how such pathways can be therapeutically targeted.

Original languageEnglish
Pages (from-to)36-50
Number of pages15
JournalCell Metabolism
Volume30
Issue number1
DOIs
Publication statusPublished - Jul 2 2019

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Keywords

  • fatty acid oxidation
  • glycolysis
  • hypoxia
  • immunosuppressive metabolites
  • immunotherapy
  • oxidative phosphorylation

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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