Macrophages and Metabolism in the Tumor Microenvironment

Ilio Vitale, Gwenola Manic, Lisa M. Coussens, Guido Kroemer, Lorenzo Galluzzi

Research output: Contribution to journalReview article

Abstract

Vitale et al. discuss the metabolic circuitries whereby tumor-associated macrophages condition their microenvironment to support the cancer growth, metastatic dissemination and resistance to treatment, and how such pathways can be therapeutically targeted.

Original languageEnglish
Pages (from-to)36-50
Number of pages15
JournalCell Metabolism
Volume30
Issue number1
DOIs
Publication statusPublished - Jul 2 2019

Fingerprint

Tumor Microenvironment
Macrophages
Neoplasms
Growth

Keywords

  • fatty acid oxidation
  • glycolysis
  • hypoxia
  • immunosuppressive metabolites
  • immunotherapy
  • oxidative phosphorylation

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

Cite this

Macrophages and Metabolism in the Tumor Microenvironment. / Vitale, Ilio; Manic, Gwenola; Coussens, Lisa M.; Kroemer, Guido; Galluzzi, Lorenzo.

In: Cell Metabolism, Vol. 30, No. 1, 02.07.2019, p. 36-50.

Research output: Contribution to journalReview article

Vitale, Ilio ; Manic, Gwenola ; Coussens, Lisa M. ; Kroemer, Guido ; Galluzzi, Lorenzo. / Macrophages and Metabolism in the Tumor Microenvironment. In: Cell Metabolism. 2019 ; Vol. 30, No. 1. pp. 36-50.
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