Macrophages give Gas(6) to cancer

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In this issue of Blood, Loges and colleagues have identified a novel tumor-promoting mechanism, whereby tumors educate tumor-associated macrophages to produce high levels of the mitogen Gas6, leading to tumor growth and metastasis.1 Surprisingly, this newly identified protumoral activity of tumor-associated macrophages is restricted to the selective induction of cancer cell proliferation, without interfering with cancer cell survival, tumor-associated inflammation, and angiogenesis.

Original languageEnglish
Pages (from-to)2122-2123
Number of pages2
JournalBlood
Volume115
Issue number11
DOIs
Publication statusPublished - Mar 11 2010

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Macrophages
Tumors
Gases
Neoplasms
Cell proliferation
Mitogens
Blood
Cells
Cell Survival
Cell Proliferation
Inflammation
Growth

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Immunology
  • Hematology

Cite this

Macrophages give Gas(6) to cancer. / Sica, Antonio.

In: Blood, Vol. 115, No. 11, 11.03.2010, p. 2122-2123.

Research output: Contribution to journalArticle

Sica, Antonio. / Macrophages give Gas(6) to cancer. In: Blood. 2010 ; Vol. 115, No. 11. pp. 2122-2123.
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