Macrophages in rheumatoid arthritis

N. Maruotti, F. P. Cantatore, E. Crivellato, A. Vacca, Domenico Ribatti

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance between proinflammatory and anti-inflammatory cytokines, an imbalance between these inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis.

Original languageEnglish
Pages (from-to)581-586
Number of pages6
JournalHistology and Histopathology
Volume22
Issue number4-6
Publication statusPublished - Apr 2007

Fingerprint

Rheumatoid Arthritis
Macrophages
Cytokines
Inflammation
Matrix Metalloproteinases
Chemokines
Intercellular Signaling Peptides and Proteins
Anti-Inflammatory Agents
Joints

Keywords

  • Chemokine
  • Cytokine
  • Macrophage
  • Metalloproteinase
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

Cite this

Maruotti, N., Cantatore, F. P., Crivellato, E., Vacca, A., & Ribatti, D. (2007). Macrophages in rheumatoid arthritis. Histology and Histopathology, 22(4-6), 581-586.

Macrophages in rheumatoid arthritis. / Maruotti, N.; Cantatore, F. P.; Crivellato, E.; Vacca, A.; Ribatti, Domenico.

In: Histology and Histopathology, Vol. 22, No. 4-6, 04.2007, p. 581-586.

Research output: Contribution to journalArticle

Maruotti, N, Cantatore, FP, Crivellato, E, Vacca, A & Ribatti, D 2007, 'Macrophages in rheumatoid arthritis', Histology and Histopathology, vol. 22, no. 4-6, pp. 581-586.
Maruotti N, Cantatore FP, Crivellato E, Vacca A, Ribatti D. Macrophages in rheumatoid arthritis. Histology and Histopathology. 2007 Apr;22(4-6):581-586.
Maruotti, N. ; Cantatore, F. P. ; Crivellato, E. ; Vacca, A. ; Ribatti, Domenico. / Macrophages in rheumatoid arthritis. In: Histology and Histopathology. 2007 ; Vol. 22, No. 4-6. pp. 581-586.
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