Macrophages in rheumatoid arthritis.

N. Maruotti; F. P. Cantatore; E. Crivellato; A. Vacca; D. Ribatti

Macrophages in rheumatoid arthritis.

N. Maruotti, F. P. Cantatore, E. Crivellato, A. Vacca, D. Ribatti

IRCCS Giovanni Paolo II

Research output: Contribution to journal › Article › peer-review

Abstract

In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance between proinflammatory and anti-inflammatory cytokines, an imbalance between these inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis.

Original language	English
Pages (from-to)	581-586
Number of pages	6
Journal	Histology and Histopathology
Volume	22
Issue number	5
Publication status	Published - May 2007

ASJC Scopus subject areas

Anatomy
Pathology and Forensic Medicine
Histology
Cell Biology

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title = "Macrophages in rheumatoid arthritis.",

abstract = "In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance between proinflammatory and anti-inflammatory cytokines, an imbalance between these inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis.",

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