Abstract
In rheumatoid arthritis (RA) tissue macrophages release growth factors, matrix metalloproteinases, cytokines, and chemokines. While in normal joints there is a balance between proinflammatory and anti-inflammatory cytokines, an imbalance between these inducers and inhibitors of inflammation occurs in RA, where macrophages are responsible for inducing inflammation, matrix destruction and angiogenesis.
Original language | English |
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Pages (from-to) | 581-586 |
Number of pages | 6 |
Journal | Histology and Histopathology |
Volume | 22 |
Issue number | 5 |
Publication status | Published - May 2007 |
ASJC Scopus subject areas
- Anatomy
- Pathology and Forensic Medicine
- Histology
- Cell Biology