Macular choroidal volume variations in highly myopic eyes with myopic traction maculopathy and choroidal neovascularization

Giulio Barteselli, Su Na Lee, Sharif El-Emam, Huiyuan Hou, Feiyan Ma, Jay Chhablani, Laura Conner, Lingyun Cheng, Dirk Uwe Bartsch, William R. Freeman

Research output: Contribution to journalArticle

Abstract

PURPOSE:: To compare the choroidal volume (CV) between emmetropic and highly myopic eyes, and to assess if the presence of myopic fundus abnormalities, myopic traction maculopathy, or choroidal neovascularization affects the CV. METHODS:: We retrospectively reviewed imaging studies of 98 eyes of 98 patients who underwent CV measurement on optical coherence tomography. We included 31 emmetropic eyes (Group 1), 36 highly myopic eyes without vitreoretinal or choroidal pathologies (Group 2), 21 highly myopic eyes with traction maculopathy (Group 3), and 10 highly myopic eyes with history of choroidal neovascularization (Group 3). Eyes with chorioretinal atrophy were excluded. Regression analysis was performed to evaluate the correlation between CV and multiple variables. RESULTS:: Choroidal volume was lower in Group 2 than in Group 1 (P <0.001), and in Groups 3 and 4 than in Group 2 (P <0.001 and P = 0.002, respectively). Age (P = 0.002), axial length (P <0.001), sex (P = 0.047), staphyloma (P <0.001), and myopic group (P = 0.05) were independent predictors for the final CV (R = 0.645). In highly myopic eyes, CV decreased by 0.32 mm for every 10 years and by 0.49 mm per millimeter of axial length. CONCLUSION:: Choroidal thinning is present in highly myopic eyes compared with emmetropic eyes, and is related to age, axial length, sex, and staphyloma. However, myopic eyes with coexisting myopic traction maculopathy or history of choroidal neovascularization have more severe thinning, likely leading to insufficient metabolic supplementation for the macula.

Original languageEnglish
Pages (from-to)880-889
Number of pages10
JournalRetina
Volume34
Issue number5
DOIs
Publication statusPublished - 2014

Keywords

  • Choroidal thickness
  • Choroidal volume
  • Enhanced depth imaging
  • High myopia
  • Myopic choroidal neovascularization
  • Myopic traction maculopathy

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

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    Barteselli, G., Lee, S. N., El-Emam, S., Hou, H., Ma, F., Chhablani, J., Conner, L., Cheng, L., Bartsch, D. U., & Freeman, W. R. (2014). Macular choroidal volume variations in highly myopic eyes with myopic traction maculopathy and choroidal neovascularization. Retina, 34(5), 880-889. https://doi.org/10.1097/IAE.0000000000000015