Macular drusen and the sensitivity of the central visual field

Edoardo Midena, Tatiana Segato, Maria Chiara Blarzino, Claudia Degli Angeli

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Macular drusen are one of the earliest signs of age-related macular degeneration but little information is available on the functional aspects of macular area in patients with drusen. To determine if drusen are associated with changes in central visual field sensitivity, one eye of each of 35 subjects (mean age 64.9 years) with bilateral drusen and visual acuity of 1.0 (20/20) underwent automated static threshold perimetry of the central 10°. 16 normal subjects (mean age 65.8 years) were used as controls. 30° fundus photographs were graded in a masked fashion for the clinical characteristics of drusen: type, size and number. The mean sensitivity (MS) of the central 10° was significantly lower in eyes with drusen compared to normal eyes (p=.0001). After grading drusen eyes for size (≥ 63 μ) and type (presence of soft drusen), MS significantly deteriorated when large and soft drusen were present. These results suggest that central visual field sensitivity is precociously affected in eyes with drusen and that testing central visual field sensitivity may be useful as functional parameter in long term studies on the evolution of age-related macular degeneration.

Original languageEnglish
Pages (from-to)179-185
Number of pages7
JournalDocumenta Ophthalmologica
Volume88
Issue number2
DOIs
Publication statusPublished - Jun 1994

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Visual Fields
Macular Degeneration
Visual Field Tests
Visual Acuity

Keywords

  • Age-related macular degeneration
  • Drusen
  • Visual field sensitivity

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Macular drusen and the sensitivity of the central visual field. / Midena, Edoardo; Segato, Tatiana; Blarzino, Maria Chiara; Angeli, Claudia Degli.

In: Documenta Ophthalmologica, Vol. 88, No. 2, 06.1994, p. 179-185.

Research output: Contribution to journalArticle

Midena, Edoardo ; Segato, Tatiana ; Blarzino, Maria Chiara ; Angeli, Claudia Degli. / Macular drusen and the sensitivity of the central visual field. In: Documenta Ophthalmologica. 1994 ; Vol. 88, No. 2. pp. 179-185.
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