Magnesium as a preventive treatment for paediatric episodic tension-type headache: Results at 1-year follow-up

Licia Grazzi, F. Andrasik, S. Usai, G. Bussone

Research output: Contribution to journalArticle


The objective was to confirm the long-term utility of magnesium salts treatment on a group of young patients suffering from episodic tension-type headache (ETTH). The study was carried out at the Outpatient Headache Center at the National Neurological Institute "C. Besta," Milan, Italy, with 45 children/adolescents with ETTH reporting consecutively for treatment. Magnesium pidolate (2.25 g) was given twice per day for three months. Medication was not administered during the year of follow-up. No other treatment was provided at any time. Patients showed significant symptom reduction. Headache days decreased by 69.9%, whereas analgesics consumption was reduced by 65.4%. Overall disability levels improved by the greatest percent - 75.7%. MIDAS subscores improved as well (question A=58.0%; question B=22.5%). Although uncontrolled, these findings are encouraging and suggest that further, better controlled research investigations are warranted.

Original languageEnglish
Pages (from-to)148-150
Number of pages3
JournalNeurological Sciences
Issue number3
Publication statusPublished - Jun 2007



  • Disability
  • Long-term follow-up
  • Magnesium pidolate
  • Tension-type headache (TTH)

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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