Magnesium-enriched hydroxyapatite compared to calcium sulfate in the healing of human extraction sockets: Radiographic and histomorphometric evaluation at 3 months

Roberto Crespi, Paolo Capparè, Enrico Gherlone

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Reduction of alveolar height and width after tooth extraction may present problems for implant placement, especially in the anterior maxilla where bone volume is important for biologic and esthetic reasons. Different graft materials have been proposed to minimize the reduction in ridge volume. The aim of this study was to compare radiographic and histomorphometric results of magnesium-enriched hydroxyapatite (MHA) and calcium sulfate (CS) grafts in fresh sockets after tooth extractions. Methods: Forty-five fresh extraction sockets with three bone walls were selected in 15 patients. A split-mouth design was used: 15 sockets on the right side of the jaw received MHA, 15 sockets on the left side received CS, and 15 random unfilled sockets were considered the control (C) group. Intraoral digital radiographs were taken at baseline and at 3 months after graft material placement. At 3 months, cylinder bone samples were obtained for histology and histomorphometry analysis. Results: The difference in mean radiographic vertical bone level from baseline to 3 months was -2.48 ± 0.65 mm in the CS group, -0.48 ± 0.21 mmin the MHA group, and -3.75 ± 0.63mmin the unfilled C group. Statistically significant differences (P

Original languageEnglish
Pages (from-to)210-218
Number of pages9
JournalJournal of Periodontology
Volume80
Issue number2
DOIs
Publication statusPublished - Feb 2009

Keywords

  • Calcium sulfate
  • Hydroxyapatite
  • Tooth extraction
  • Wound healing

ASJC Scopus subject areas

  • Periodontics

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