Abstract
Quality of life of craniopharyngioma patients can be severely impaired by derangement of hypothalamic function. A classification, taking into account preoperative hypothalamic damage, evaluated by magnetic resonance imaging (MRI), and correlating it with postoperative weight change is still missing in the literature. The aim of our study is to identify objective radiological criteria as preoperative prognostic factors for hypothalamic damage. Pre- and post-operative MRI and clinical data of 47 patients, treated at our Institution for craniopharyngioma, were retrospectively analyzed, based on radiological variables, identified as prognostic factor for hypothalamic involvement. Main factors associated with postoperative obesity were hypothalamic hyperintensity in T2-weighted/FLAIR imaging (p
Original language | English |
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Pages (from-to) | 148-162 |
Number of pages | 15 |
Journal | Endocrine |
Volume | 51 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 1 2016 |
Keywords
- Clinical outcome
- Craniopharyngioma
- Hypothalamus
- MRI
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism