Abstract
Quality of life of craniopharyngioma patients can be severely impaired by derangement of hypothalamic function. A classification, taking into account preoperative hypothalamic damage, evaluated by magnetic resonance imaging (MRI), and correlating it with postoperative weight change is still missing in the literature. The aim of our study is to identify objective radiological criteria as preoperative prognostic factors for hypothalamic damage. Pre- and post-operative MRI and clinical data of 47 patients, treated at our Institution for craniopharyngioma, were retrospectively analyzed, based on radiological variables, identified as prognostic factor for hypothalamic involvement. Main factors associated with postoperative obesity were hypothalamic hyperintensity in T2-weighted/FLAIR imaging (p
| Original language | English |
|---|---|
| Pages (from-to) | 148-162 |
| Number of pages | 15 |
| Journal | Endocrine |
| Volume | 51 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2016 |
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Keywords
- Clinical outcome
- Craniopharyngioma
- Hypothalamus
- MRI
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Magnetic resonance imaging as predictor of functional outcome in craniopharyngiomas. / Mortini, Pietro; Gagliardi, Filippo; Bailo, Michele; Spina, Alfio; Parlangeli, Andrea; Falini, Andrea; Losa, Marco.
In: Endocrine, Vol. 51, No. 1, 01.01.2016, p. 148-162.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Magnetic resonance imaging as predictor of functional outcome in craniopharyngiomas
AU - Mortini, Pietro
AU - Gagliardi, Filippo
AU - Bailo, Michele
AU - Spina, Alfio
AU - Parlangeli, Andrea
AU - Falini, Andrea
AU - Losa, Marco
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Quality of life of craniopharyngioma patients can be severely impaired by derangement of hypothalamic function. A classification, taking into account preoperative hypothalamic damage, evaluated by magnetic resonance imaging (MRI), and correlating it with postoperative weight change is still missing in the literature. The aim of our study is to identify objective radiological criteria as preoperative prognostic factors for hypothalamic damage. Pre- and post-operative MRI and clinical data of 47 patients, treated at our Institution for craniopharyngioma, were retrospectively analyzed, based on radiological variables, identified as prognostic factor for hypothalamic involvement. Main factors associated with postoperative obesity were hypothalamic hyperintensity in T2-weighted/FLAIR imaging (p
AB - Quality of life of craniopharyngioma patients can be severely impaired by derangement of hypothalamic function. A classification, taking into account preoperative hypothalamic damage, evaluated by magnetic resonance imaging (MRI), and correlating it with postoperative weight change is still missing in the literature. The aim of our study is to identify objective radiological criteria as preoperative prognostic factors for hypothalamic damage. Pre- and post-operative MRI and clinical data of 47 patients, treated at our Institution for craniopharyngioma, were retrospectively analyzed, based on radiological variables, identified as prognostic factor for hypothalamic involvement. Main factors associated with postoperative obesity were hypothalamic hyperintensity in T2-weighted/FLAIR imaging (p
KW - Clinical outcome
KW - Craniopharyngioma
KW - Hypothalamus
KW - MRI
UR - http://www.scopus.com/inward/record.url?scp=84953840170&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84953840170&partnerID=8YFLogxK
U2 - 10.1007/s12020-015-0683-x
DO - 10.1007/s12020-015-0683-x
M3 - Article
AN - SCOPUS:84953840170
VL - 51
SP - 148
EP - 162
JO - Endocrine
JF - Endocrine
SN - 1355-008X
IS - 1
ER -