Magnetic resonance imaging as predictor of functional outcome in craniopharyngiomas

Pietro Mortini; Filippo Gagliardi; Michele Bailo; Alfio Spina; Andrea Parlangeli; Andrea Falini; Marco Losa

doi:10.1007/s12020-015-0683-x

Magnetic resonance imaging as predictor of functional outcome in craniopharyngiomas

Pietro Mortini, Filippo Gagliardi, Michele Bailo, Alfio Spina, Andrea Parlangeli, Andrea Falini, Marco Losa

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Quality of life of craniopharyngioma patients can be severely impaired by derangement of hypothalamic function. A classification, taking into account preoperative hypothalamic damage, evaluated by magnetic resonance imaging (MRI), and correlating it with postoperative weight change is still missing in the literature. The aim of our study is to identify objective radiological criteria as preoperative prognostic factors for hypothalamic damage. Pre- and post-operative MRI and clinical data of 47 patients, treated at our Institution for craniopharyngioma, were retrospectively analyzed, based on radiological variables, identified as prognostic factor for hypothalamic involvement. Main factors associated with postoperative obesity were hypothalamic hyperintensity in T2-weighted/FLAIR imaging (p

Original language	English
Pages (from-to)	148-162
Number of pages	15
Journal	Endocrine
Volume	51
Issue number	1
DOIs	https://doi.org/10.1007/s12020-015-0683-x
Publication status	Published - Jan 1 2016

Keywords

Clinical outcome
Craniopharyngioma
Hypothalamus
MRI

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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abstract = "Quality of life of craniopharyngioma patients can be severely impaired by derangement of hypothalamic function. A classification, taking into account preoperative hypothalamic damage, evaluated by magnetic resonance imaging (MRI), and correlating it with postoperative weight change is still missing in the literature. The aim of our study is to identify objective radiological criteria as preoperative prognostic factors for hypothalamic damage. Pre- and post-operative MRI and clinical data of 47 patients, treated at our Institution for craniopharyngioma, were retrospectively analyzed, based on radiological variables, identified as prognostic factor for hypothalamic involvement. Main factors associated with postoperative obesity were hypothalamic hyperintensity in T2-weighted/FLAIR imaging (p ",

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AU - Mortini, Pietro

AU - Gagliardi, Filippo

AU - Bailo, Michele

AU - Spina, Alfio

AU - Parlangeli, Andrea

AU - Falini, Andrea

AU - Losa, Marco

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Magnetic resonance imaging as predictor of functional outcome in craniopharyngiomas

Abstract

Keywords

ASJC Scopus subject areas

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