La risonanza magnetica nello studio delle neoplasie surrenaliche: Analisi qualitativa e quantitativa dell'intensita del segnale

Translated title of the contribution: Magnetic resonance imaging at adrenal masses: Qualitative and quantitative analyses of signal intensity

S. Maurea, C. Caraco, L. Castelli, S. Filice, B. Alfano, F. Ruffolo, M. Ziviello, M. Salvatore

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction. Magnetic resonance imaging (MRI) has been proposed as the diagnostic technique of choice to characterize adrenal tumors. However, the results of the current studies are controversial. Material and methods. Forty-nine patients with unilateral adrenal masses were submitted to MRI for lesion characterization on the basis of MRI signal intensity. Cytology and/or histology demonstrated 14 pheochromocytomas (pheos), 11 adenomas, 3 cysts, 2 myelolipomas, 4 carcinomas, 3 metastases and 1 fibrosarcoma; a clinical diagnosis of adenoma was made in the remaining 11 patients. MR studies were performed using spin-echo (SE) sequences with T1 (TR/TE = 600/17 ms) and T2 (TR/TE = 2000/15-90 ms) weighting. T1-weighted images were also acquired after Gadolinium-DTPA (Gd-DTPA) administration. MR studies were integrated with in- and out-of-phase (TR/TE = 100/4-6 ms) chemical-shift (CS) sequences. MR signal intensity (SI) was analyzed qualitatively and quantitatively; MR results were correlated with tumor type and hormone secretion. Results. The qualitative analysis of T2 images showed high signal intensity in the majority (80%) of adrenal lesions (14 pheos, 12 adenomas, 3 cysts, 2 myelolipomas and 8 malignancies). The quantitative analysis of post-Gd-DTPA T1 images permitted to distinguish adenomas, cysts and myelolipomas from pheos and malignancies. The qualitative analysis of post-Gd-DTPA T2 and T1 images permitted to distinguish pheos and cysts from adenomas and malignancies (p

Translated title of the contributionMagnetic resonance imaging at adrenal masses: Qualitative and quantitative analyses of signal intensity
Original languageItalian
Pages (from-to)199-207
Number of pages9
JournalRadiologia Medica
Volume95
Issue number3
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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