La risonanza magnetica nello studio delle neoplasie surrenaliche: Analisi qualitativa e quantitativa dell'intensita del segnale

Translated title of the contribution: Magnetic resonance imaging at adrenal masses: Qualitative and quantitative analyses of signal intensity

S. Maurea, C. Caraco, L. Castelli, S. Filice, B. Alfano, F. Ruffolo, M. Ziviello, M. Salvatore

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction. Magnetic resonance imaging (MRI) has been proposed as the diagnostic technique of choice to characterize adrenal tumors. However, the results of the current studies are controversial. Material and methods. Forty-nine patients with unilateral adrenal masses were submitted to MRI for lesion characterization on the basis of MRI signal intensity. Cytology and/or histology demonstrated 14 pheochromocytomas (pheos), 11 adenomas, 3 cysts, 2 myelolipomas, 4 carcinomas, 3 metastases and 1 fibrosarcoma; a clinical diagnosis of adenoma was made in the remaining 11 patients. MR studies were performed using spin-echo (SE) sequences with T1 (TR/TE = 600/17 ms) and T2 (TR/TE = 2000/15-90 ms) weighting. T1-weighted images were also acquired after Gadolinium-DTPA (Gd-DTPA) administration. MR studies were integrated with in- and out-of-phase (TR/TE = 100/4-6 ms) chemical-shift (CS) sequences. MR signal intensity (SI) was analyzed qualitatively and quantitatively; MR results were correlated with tumor type and hormone secretion. Results. The qualitative analysis of T2 images showed high signal intensity in the majority (80%) of adrenal lesions (14 pheos, 12 adenomas, 3 cysts, 2 myelolipomas and 8 malignancies). The quantitative analysis of post-Gd-DTPA T1 images permitted to distinguish adenomas, cysts and myelolipomas from pheos and malignancies. The qualitative analysis of post-Gd-DTPA T2 and T1 images permitted to distinguish pheos and cysts from adenomas and malignancies (p

Original languageItalian
Pages (from-to)199-207
Number of pages9
JournalRadiologia Medica
Volume95
Issue number3
Publication statusPublished - 1998

Fingerprint

Adenoma
Myelolipoma
Pheochromocytoma
Gadolinium DTPA
Magnetic Resonance Imaging
Cysts
Neoplasms
Glandular and Epithelial Neoplasms
Fibrosarcoma
Cell Biology
Histology
Hormones
Neoplasm Metastasis
Carcinoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

La risonanza magnetica nello studio delle neoplasie surrenaliche : Analisi qualitativa e quantitativa dell'intensita del segnale. / Maurea, S.; Caraco, C.; Castelli, L.; Filice, S.; Alfano, B.; Ruffolo, F.; Ziviello, M.; Salvatore, M.

In: Radiologia Medica, Vol. 95, No. 3, 1998, p. 199-207.

Research output: Contribution to journalArticle

Maurea, S. ; Caraco, C. ; Castelli, L. ; Filice, S. ; Alfano, B. ; Ruffolo, F. ; Ziviello, M. ; Salvatore, M. / La risonanza magnetica nello studio delle neoplasie surrenaliche : Analisi qualitativa e quantitativa dell'intensita del segnale. In: Radiologia Medica. 1998 ; Vol. 95, No. 3. pp. 199-207.
@article{c9d0dec8b62944bfa89721e4b2da0768,
title = "La risonanza magnetica nello studio delle neoplasie surrenaliche: Analisi qualitativa e quantitativa dell'intensita del segnale",
abstract = "Introduction. Magnetic resonance imaging (MRI) has been proposed as the diagnostic technique of choice to characterize adrenal tumors. However, the results of the current studies are controversial. Material and methods. Forty-nine patients with unilateral adrenal masses were submitted to MRI for lesion characterization on the basis of MRI signal intensity. Cytology and/or histology demonstrated 14 pheochromocytomas (pheos), 11 adenomas, 3 cysts, 2 myelolipomas, 4 carcinomas, 3 metastases and 1 fibrosarcoma; a clinical diagnosis of adenoma was made in the remaining 11 patients. MR studies were performed using spin-echo (SE) sequences with T1 (TR/TE = 600/17 ms) and T2 (TR/TE = 2000/15-90 ms) weighting. T1-weighted images were also acquired after Gadolinium-DTPA (Gd-DTPA) administration. MR studies were integrated with in- and out-of-phase (TR/TE = 100/4-6 ms) chemical-shift (CS) sequences. MR signal intensity (SI) was analyzed qualitatively and quantitatively; MR results were correlated with tumor type and hormone secretion. Results. The qualitative analysis of T2 images showed high signal intensity in the majority (80{\%}) of adrenal lesions (14 pheos, 12 adenomas, 3 cysts, 2 myelolipomas and 8 malignancies). The quantitative analysis of post-Gd-DTPA T1 images permitted to distinguish adenomas, cysts and myelolipomas from pheos and malignancies. The qualitative analysis of post-Gd-DTPA T2 and T1 images permitted to distinguish pheos and cysts from adenomas and malignancies (p",
keywords = "Adrenal gland, Chemical-shift sequences, Gd-DTPA - MRI, Tumors - MRI",
author = "S. Maurea and C. Caraco and L. Castelli and S. Filice and B. Alfano and F. Ruffolo and M. Ziviello and M. Salvatore",
year = "1998",
language = "Italian",
volume = "95",
pages = "199--207",
journal = "Radiologia Medica",
issn = "0033-8362",
publisher = "Springer-Verlag Italia s.r.l.",
number = "3",

}

TY - JOUR

T1 - La risonanza magnetica nello studio delle neoplasie surrenaliche

T2 - Analisi qualitativa e quantitativa dell'intensita del segnale

AU - Maurea, S.

AU - Caraco, C.

AU - Castelli, L.

AU - Filice, S.

AU - Alfano, B.

AU - Ruffolo, F.

AU - Ziviello, M.

AU - Salvatore, M.

PY - 1998

Y1 - 1998

N2 - Introduction. Magnetic resonance imaging (MRI) has been proposed as the diagnostic technique of choice to characterize adrenal tumors. However, the results of the current studies are controversial. Material and methods. Forty-nine patients with unilateral adrenal masses were submitted to MRI for lesion characterization on the basis of MRI signal intensity. Cytology and/or histology demonstrated 14 pheochromocytomas (pheos), 11 adenomas, 3 cysts, 2 myelolipomas, 4 carcinomas, 3 metastases and 1 fibrosarcoma; a clinical diagnosis of adenoma was made in the remaining 11 patients. MR studies were performed using spin-echo (SE) sequences with T1 (TR/TE = 600/17 ms) and T2 (TR/TE = 2000/15-90 ms) weighting. T1-weighted images were also acquired after Gadolinium-DTPA (Gd-DTPA) administration. MR studies were integrated with in- and out-of-phase (TR/TE = 100/4-6 ms) chemical-shift (CS) sequences. MR signal intensity (SI) was analyzed qualitatively and quantitatively; MR results were correlated with tumor type and hormone secretion. Results. The qualitative analysis of T2 images showed high signal intensity in the majority (80%) of adrenal lesions (14 pheos, 12 adenomas, 3 cysts, 2 myelolipomas and 8 malignancies). The quantitative analysis of post-Gd-DTPA T1 images permitted to distinguish adenomas, cysts and myelolipomas from pheos and malignancies. The qualitative analysis of post-Gd-DTPA T2 and T1 images permitted to distinguish pheos and cysts from adenomas and malignancies (p

AB - Introduction. Magnetic resonance imaging (MRI) has been proposed as the diagnostic technique of choice to characterize adrenal tumors. However, the results of the current studies are controversial. Material and methods. Forty-nine patients with unilateral adrenal masses were submitted to MRI for lesion characterization on the basis of MRI signal intensity. Cytology and/or histology demonstrated 14 pheochromocytomas (pheos), 11 adenomas, 3 cysts, 2 myelolipomas, 4 carcinomas, 3 metastases and 1 fibrosarcoma; a clinical diagnosis of adenoma was made in the remaining 11 patients. MR studies were performed using spin-echo (SE) sequences with T1 (TR/TE = 600/17 ms) and T2 (TR/TE = 2000/15-90 ms) weighting. T1-weighted images were also acquired after Gadolinium-DTPA (Gd-DTPA) administration. MR studies were integrated with in- and out-of-phase (TR/TE = 100/4-6 ms) chemical-shift (CS) sequences. MR signal intensity (SI) was analyzed qualitatively and quantitatively; MR results were correlated with tumor type and hormone secretion. Results. The qualitative analysis of T2 images showed high signal intensity in the majority (80%) of adrenal lesions (14 pheos, 12 adenomas, 3 cysts, 2 myelolipomas and 8 malignancies). The quantitative analysis of post-Gd-DTPA T1 images permitted to distinguish adenomas, cysts and myelolipomas from pheos and malignancies. The qualitative analysis of post-Gd-DTPA T2 and T1 images permitted to distinguish pheos and cysts from adenomas and malignancies (p

KW - Adrenal gland

KW - Chemical-shift sequences

KW - Gd-DTPA - MRI

KW - Tumors - MRI

UR - http://www.scopus.com/inward/record.url?scp=0031800138&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031800138&partnerID=8YFLogxK

M3 - Articolo

C2 - 9638166

AN - SCOPUS:0031800138

VL - 95

SP - 199

EP - 207

JO - Radiologia Medica

JF - Radiologia Medica

SN - 0033-8362

IS - 3

ER -