La Risonanza Magnetica nella valutazione dell'invasione parametriale nel carcinoma della cervice uterina Ottimizzazione del protocollo di studio

Translated title of the contribution: Magnetic Resonance Imaging in the evaluation of parametrial invasion from carcinoma of the cervix: Comparison of different pulse sequences

Sandro Sironi, Gaetano Villa, Silvia Rossi, Luca Bocciolone, Angelo Maggioni, Angelica Sonzogni, Massimo Bellomi

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose. To determine the efficacy of three different MR sequences in the evaluation of parametrial invasion by early-stage cervical cancer. Material and methods. Eighteen consecutive patients with cervical cancer clinically assessed as stage IB1 underwent MR imaging examination with the use of the following sequences: FSE T2-weighted, FSE fat-suppressed T2w, and SE fat-suppressed Gadolinium-enhanced T1w. In all cases, the presence or absence of parametrial invasion on both sides per each sequence used was evaluated. Subsequently all the sequences have been considered together for the evaluation of tumor invasion. Gold standard of the study was the histopathologic analysis of the surgical specimens. Results. At histological examination, parametrial invasion by tumor was found in 6 out of 36 parametria evaluated. The accuracy achieved with each of the sequences used was as follows: 94% with FSE T2w; 86% with FSE fat-suppressed T2w; and 67% with SE fat-suppressed Gadolinium-enhanced T1w. The simultaneous evaluation of all 3 sequences obtained an accuracy level similar to that achieved with FSE T2w. The difference between the accuracy of T2w sequences and that of fat-suppressed contrast-enhanced T1w sequences was statistically significant (p

Translated title of the contributionMagnetic Resonance Imaging in the evaluation of parametrial invasion from carcinoma of the cervix: Comparison of different pulse sequences
Original languageItalian
Pages (from-to)477-484
Number of pages8
JournalRadiologia Medica
Volume101
Issue number6
Publication statusPublished - Jun 2001

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Magnetic Resonance Imaging in the evaluation of parametrial invasion from carcinoma of the cervix: Comparison of different pulse sequences'. Together they form a unique fingerprint.

Cite this