Magnetic resonance imaging of fetal cerebellar development

Fabio Triulzi, Cecilia Parazzini, Andrea Righini

Research output: Contribution to journalArticle

Abstract

In the last few years fetal magnetic resonance imaging (MRI) has been proposed as a second level technique in the evaluation of fetal brain anomalies. It has been demonstrated that MRI is highly accurate in illustrating the morphologic changes of developing brain and fetal brain abnormalities being a useful procedure when ultrasonography is inconclusive or doubtful. Starting from the 19-20 weeks gestational age (GA), MRI can reliably depict fetal brain anatomy and locating pathology, offering a robust and reliable tool in the assessment of fetal CNS diseases. In this review both in vivo MRI quantitative and qualitative data about fetal cerebellar development are presented and compared with ultrasonography data. Fetal cerebellar development is gradual, steady, and largely comparable to the development of the supratentorial brain. Archicerebellar (flocculo-nodular lobe) and paleocerebellar (vermis) structures develop first, whereas neocerebellum (cerebellar hemispheres) develop slowly and largely after birth.

Original languageEnglish
Pages (from-to)199-205
Number of pages7
JournalCerebellum
Volume5
Issue number3
DOIs
Publication statusPublished - Sep 1 2006

Keywords

  • Cerebellar development
  • CNS anatomy
  • Fetal MRI

ASJC Scopus subject areas

  • Neuroscience(all)

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