Magnetic Resonance Spectroscopy in Metabolic Disorders

Andrea Rossi, Roberta Biancheri

Research output: Contribution to journalArticlepeer-review


Magnetic resonance spectroscopy (MRS) is a powerful clinical tool for investigating the metabolic characteristics of neurologic diseases. Proton (1H)-MRS is the most commonly used and widely available method. In this article, a brief introduction regarding technical issues of 1H-MRS applied to the study of metabolic diseases is followed by a description of findings in some of the most common entities in this large, heterogeneous group of neurologic disorders. The aim was to provide a focused representation of the most common applications of 1H-MRS to metabolic disorders in a routine clinical setting.

Original languageEnglish
Pages (from-to)425-448
Number of pages24
JournalNeuroimaging Clinics of North America
Issue number3
Publication statusPublished - Aug 2013


  • Hypomyelination
  • Leukodystrophy
  • Leukoencephalopathy
  • Metabolic diseases
  • MR spectroscopy
  • White matter

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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