TY - JOUR
T1 - Maitotoxin and BAY-K-8644
T2 - two putative calcium channel activators with different effects on endogenous dopamine release from tuberoinfundibular neurons
AU - Taglialatela, Maurizio
AU - Amoroso, Salvatore
AU - Yasumoto, Takeshi
AU - Renzo, Gianfranco Di
AU - Annunziato, Lucio
PY - 1986/9/3
Y1 - 1986/9/3
N2 - In the present study report on the effects of two putative calcium channel activators, maitotoxin and the dihydropyridine BAY-K-8644, on endogenous dopamine release from tubeeroinfundibular dopaminergic neurons. Maitotoxin stimulated basal dopamine release and this effect was calcium-dependent. By contrast BAY-K-8644,failed to produce any modification of basal or high potassium-induced dopamine release. These results suggest that maitotoxin, unlike BAY-K-8644, represents a suitable tool to investigate the functional role of calcium channels in central dopaminergic neurons.
AB - In the present study report on the effects of two putative calcium channel activators, maitotoxin and the dihydropyridine BAY-K-8644, on endogenous dopamine release from tubeeroinfundibular dopaminergic neurons. Maitotoxin stimulated basal dopamine release and this effect was calcium-dependent. By contrast BAY-K-8644,failed to produce any modification of basal or high potassium-induced dopamine release. These results suggest that maitotoxin, unlike BAY-K-8644, represents a suitable tool to investigate the functional role of calcium channels in central dopaminergic neurons.
UR - http://www.scopus.com/inward/record.url?scp=0022474329&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022474329&partnerID=8YFLogxK
U2 - 10.1016/0006-8993(86)90088-0
DO - 10.1016/0006-8993(86)90088-0
M3 - Article
C2 - 2428437
AN - SCOPUS:0022474329
VL - 381
SP - 356
EP - 358
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 2
ER -