Malakoplakia of the pancreas with diffuse lymph-node involvement

Paolo Giovanni Nuciforo, Laura Moneghini, Paola Braidotti, Laura Castoldi, Paolo De Rai, Silvano Bosari

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We report a case of malakoplakia involving the pancreas in a 74-year-old man with associated regional lymphoadenopathy. Histological examination of both pancreas and lymph nodes revealed a diffuse histiocytic infiltrate containing numerous Michaelis-Gutmann bodies. Electron microscopy supported the diagnosis of malakoplakia and showed bacterial-like structures. Differential diagnosis includes myofibroblastic inflammatory tumor and histiocytic neoplasms. Lymph-node involvement during malakoplakia is extremely rare and it has never been documented microscopically. Lymphohematogenous spread of bacteria may be the cause of the nodal involvement, which, however, does not appear to influence the clinical course of the disease.

Original languageEnglish
Pages (from-to)82-85
Number of pages4
JournalVirchows Archiv
Volume442
Issue number1
Publication statusPublished - Jan 1 2003

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Malacoplakia
Pancreas
Lymph Nodes
Bacterial Structures
Neoplasms
Electron Microscopy
Differential Diagnosis
Bacteria

Keywords

  • Lymph nodes
  • Malakoplakia
  • Pancreas

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Nuciforo, P. G., Moneghini, L., Braidotti, P., Castoldi, L., De Rai, P., & Bosari, S. (2003). Malakoplakia of the pancreas with diffuse lymph-node involvement. Virchows Archiv, 442(1), 82-85.

Malakoplakia of the pancreas with diffuse lymph-node involvement. / Nuciforo, Paolo Giovanni; Moneghini, Laura; Braidotti, Paola; Castoldi, Laura; De Rai, Paolo; Bosari, Silvano.

In: Virchows Archiv, Vol. 442, No. 1, 01.01.2003, p. 82-85.

Research output: Contribution to journalArticle

Nuciforo, PG, Moneghini, L, Braidotti, P, Castoldi, L, De Rai, P & Bosari, S 2003, 'Malakoplakia of the pancreas with diffuse lymph-node involvement', Virchows Archiv, vol. 442, no. 1, pp. 82-85.
Nuciforo PG, Moneghini L, Braidotti P, Castoldi L, De Rai P, Bosari S. Malakoplakia of the pancreas with diffuse lymph-node involvement. Virchows Archiv. 2003 Jan 1;442(1):82-85.
Nuciforo, Paolo Giovanni ; Moneghini, Laura ; Braidotti, Paola ; Castoldi, Laura ; De Rai, Paolo ; Bosari, Silvano. / Malakoplakia of the pancreas with diffuse lymph-node involvement. In: Virchows Archiv. 2003 ; Vol. 442, No. 1. pp. 82-85.
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