Male impotence: A possible beta-adrenergic dysfunction in some patients

L. Ferini-Strambi, M. Zucconi, P. Rigatti, M. Grasso, F. Montorsi, S. Smirne

Research output: Contribution to journalArticlepeer-review


In some patients nocturnal penile tumescence (NPT) is abnormal, while the others diagnostic evaluations and medical history do not indicate any specific organic cause of impotence. Aim of this study was to evaluate heart rate variability during sleep in impotent patients with any demonstrable organic cause of impotence. We studied 50 patients: 26 were psychogenic and 24 organic on the basis of NPT and nocturnal rigidity. A lower orthosympathetic activity has been found in organic patients. Because beta-adrenergic receptors mediate relaxation of corpus cavernosum, it could be hypothesized a penile beta-adrenergic dysfunction in our organic patients.

Original languageEnglish
Pages (from-to)332-334
Number of pages3
JournalEuropean Urology
Issue number4
Publication statusPublished - 1992


  • Autonomic dysfunction
  • Male impotence

ASJC Scopus subject areas

  • Urology


Dive into the research topics of 'Male impotence: A possible beta-adrenergic dysfunction in some patients'. Together they form a unique fingerprint.

Cite this