Malignant adenoma: Diagnosis, staging, risk factors, lymph node involvement and problems of sampling

M. Risio, R. Fiocca

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Colorectal adenoma containing invasive carcinoma corresponds to a carcinoma invading the submucosa and represents the earliest form of clinically relevant colon cancer. Despite the generally favourable course after endoscopic removal, a limited risk of developing lymph node metastases still exists and the correct histologic assessment of malignant polyps can help in defining the evolutive potential. At present, histopathologic parameters alone determine whether a high (35%) or low (7%) risk of nodal metastases exists and the most relevant diagnostic criteria are the grade of differentiation of invasive adenocarcinoma, vascular invasion, the level of invasion of carcinomatous cells and the status of the resection margin.

Original languageEnglish
JournalTechniques in Coloproctology
Volume8
Issue numberSUPPL. 2
DOIs
Publication statusPublished - Dec 2004

Fingerprint

Adenocarcinoma
Lymph Nodes
Neoplasm Metastasis
Carcinoma
Polyps
Adenoma
Colonic Neoplasms
Blood Vessels
Neoplasms
Margins of Excision

Keywords

  • Adenoma
  • Cancerogenesis
  • Colon carcinoma

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

Cite this

Malignant adenoma : Diagnosis, staging, risk factors, lymph node involvement and problems of sampling. / Risio, M.; Fiocca, R.

In: Techniques in Coloproctology, Vol. 8, No. SUPPL. 2, 12.2004.

Research output: Contribution to journalArticle

@article{4c4f7c94837244d38179f9a4c41b1b55,
title = "Malignant adenoma: Diagnosis, staging, risk factors, lymph node involvement and problems of sampling",
abstract = "Colorectal adenoma containing invasive carcinoma corresponds to a carcinoma invading the submucosa and represents the earliest form of clinically relevant colon cancer. Despite the generally favourable course after endoscopic removal, a limited risk of developing lymph node metastases still exists and the correct histologic assessment of malignant polyps can help in defining the evolutive potential. At present, histopathologic parameters alone determine whether a high (35{\%}) or low (7{\%}) risk of nodal metastases exists and the most relevant diagnostic criteria are the grade of differentiation of invasive adenocarcinoma, vascular invasion, the level of invasion of carcinomatous cells and the status of the resection margin.",
keywords = "Adenoma, Cancerogenesis, Colon carcinoma",
author = "M. Risio and R. Fiocca",
year = "2004",
month = "12",
doi = "10.1007/s10151-004-0171-4",
language = "English",
volume = "8",
journal = "Techniques in Coloproctology",
issn = "1123-6337",
publisher = "Springer-Verlag Italia s.r.l.",
number = "SUPPL. 2",

}

TY - JOUR

T1 - Malignant adenoma

T2 - Diagnosis, staging, risk factors, lymph node involvement and problems of sampling

AU - Risio, M.

AU - Fiocca, R.

PY - 2004/12

Y1 - 2004/12

N2 - Colorectal adenoma containing invasive carcinoma corresponds to a carcinoma invading the submucosa and represents the earliest form of clinically relevant colon cancer. Despite the generally favourable course after endoscopic removal, a limited risk of developing lymph node metastases still exists and the correct histologic assessment of malignant polyps can help in defining the evolutive potential. At present, histopathologic parameters alone determine whether a high (35%) or low (7%) risk of nodal metastases exists and the most relevant diagnostic criteria are the grade of differentiation of invasive adenocarcinoma, vascular invasion, the level of invasion of carcinomatous cells and the status of the resection margin.

AB - Colorectal adenoma containing invasive carcinoma corresponds to a carcinoma invading the submucosa and represents the earliest form of clinically relevant colon cancer. Despite the generally favourable course after endoscopic removal, a limited risk of developing lymph node metastases still exists and the correct histologic assessment of malignant polyps can help in defining the evolutive potential. At present, histopathologic parameters alone determine whether a high (35%) or low (7%) risk of nodal metastases exists and the most relevant diagnostic criteria are the grade of differentiation of invasive adenocarcinoma, vascular invasion, the level of invasion of carcinomatous cells and the status of the resection margin.

KW - Adenoma

KW - Cancerogenesis

KW - Colon carcinoma

UR - http://www.scopus.com/inward/record.url?scp=13444306505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13444306505&partnerID=8YFLogxK

U2 - 10.1007/s10151-004-0171-4

DO - 10.1007/s10151-004-0171-4

M3 - Article

C2 - 15666101

AN - SCOPUS:13444306505

VL - 8

JO - Techniques in Coloproctology

JF - Techniques in Coloproctology

SN - 1123-6337

IS - SUPPL. 2

ER -