Abstract
Seventy-eight cases of malignant fibrous histiocytoma (MFH) of soft tissue are reported. All tumors were deeply located in the extremities. An analysis is presented with regard to sex, age, site, macro- and microscopic features. The staging was assessed according to Enneking's classification (IB, one case; IIA, 25 cases; IIB, 42 cases; III, 10 cases). The recurrence rate after surgical treatment was high (37.5%) with significant differences after inadequate surgery (70%), wide excision (38%), or amputation (0%). Adjunctive radiotherapy rarely was effective in preventing local recurrence. The overall 5-year survival rate was 36%. The prognosis was worse in (1) tumors larger than 5 cm in diameter, (2) tumors that recurred early (less than 1 year) after surgery, and (3) tumors that had inadequate surgical treatment (intralesional or marginal excision).
| Original language | English |
|---|---|
| Pages (from-to) | 356-367 |
| Number of pages | 12 |
| Journal | Cancer |
| Volume | 56 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1985 |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
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Malignant fibrous histiocytoma of soft tissue. An analysis of 78 cases located and deeply seated in the extremities. / Bertoni, F.; Capanna, R.; Biagini, R.; Bacchini, P.; Guerra, A.; Ruggieri, P.; Present, D.; Campanacci, M.
In: Cancer, Vol. 56, No. 2, 1985, p. 356-367.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Malignant fibrous histiocytoma of soft tissue. An analysis of 78 cases located and deeply seated in the extremities
AU - Bertoni, F.
AU - Capanna, R.
AU - Biagini, R.
AU - Bacchini, P.
AU - Guerra, A.
AU - Ruggieri, P.
AU - Present, D.
AU - Campanacci, M.
PY - 1985
Y1 - 1985
N2 - Seventy-eight cases of malignant fibrous histiocytoma (MFH) of soft tissue are reported. All tumors were deeply located in the extremities. An analysis is presented with regard to sex, age, site, macro- and microscopic features. The staging was assessed according to Enneking's classification (IB, one case; IIA, 25 cases; IIB, 42 cases; III, 10 cases). The recurrence rate after surgical treatment was high (37.5%) with significant differences after inadequate surgery (70%), wide excision (38%), or amputation (0%). Adjunctive radiotherapy rarely was effective in preventing local recurrence. The overall 5-year survival rate was 36%. The prognosis was worse in (1) tumors larger than 5 cm in diameter, (2) tumors that recurred early (less than 1 year) after surgery, and (3) tumors that had inadequate surgical treatment (intralesional or marginal excision).
AB - Seventy-eight cases of malignant fibrous histiocytoma (MFH) of soft tissue are reported. All tumors were deeply located in the extremities. An analysis is presented with regard to sex, age, site, macro- and microscopic features. The staging was assessed according to Enneking's classification (IB, one case; IIA, 25 cases; IIB, 42 cases; III, 10 cases). The recurrence rate after surgical treatment was high (37.5%) with significant differences after inadequate surgery (70%), wide excision (38%), or amputation (0%). Adjunctive radiotherapy rarely was effective in preventing local recurrence. The overall 5-year survival rate was 36%. The prognosis was worse in (1) tumors larger than 5 cm in diameter, (2) tumors that recurred early (less than 1 year) after surgery, and (3) tumors that had inadequate surgical treatment (intralesional or marginal excision).
UR - http://www.scopus.com/inward/record.url?scp=0021878798&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021878798&partnerID=8YFLogxK
U2 - 10.1002/1097-0142(19850715)56:2<356::AID-CNCR2820560226>3.0.CO;2-E
DO - 10.1002/1097-0142(19850715)56:2<356::AID-CNCR2820560226>3.0.CO;2-E
M3 - Article
C2 - 2988743
AN - SCOPUS:0021878798
VL - 56
SP - 356
EP - 367
JO - Cancer
JF - Cancer
SN - 0008-543X
IS - 2
ER -