Abstract
Vaginal melanoma (VM) is a rare disease comprising, 1% of all melanomas among women, and about 3% of all vaginal malignancies. Patients experience a poor prognosis, showing, 15% 5-year survival. The report concerns two premenopausal patients with VM treated by surgery with radical intent. The first patient presented with a large lesion also infiltrating the proximal paracolpium and the bladder. The second patient had a persistent lesion of the lower third of the vagina. However, in the absence of any evidence-based guidelines or even clear suggestions from the literature, it is reasonable to believe that an appropriate management of primary malignant VM should address the radical tumor resection with wide tumor-free surgical margins and symptom relief.
| Original language | English |
|---|---|
| Pages (from-to) | 120-125 |
| Number of pages | 6 |
| Journal | International Surgery |
| Volume | 95 |
| Issue number | 2 |
| Publication status | Published - Apr 2010 |
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Keywords
- Gynecological cancer
- Vaginal malignancies
- Vaginal melanoma
ASJC Scopus subject areas
- Surgery
Cite this
Malignant melanoma of the vagina : Report of two cases and review of the literature. / Greggi, Stefano; Losito, Simona; Pisano, Carmela; Desicato, Sonia; Scaffa, Cono.
In: International Surgery, Vol. 95, No. 2, 04.2010, p. 120-125.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Malignant melanoma of the vagina
T2 - Report of two cases and review of the literature
AU - Greggi, Stefano
AU - Losito, Simona
AU - Pisano, Carmela
AU - Desicato, Sonia
AU - Scaffa, Cono
PY - 2010/4
Y1 - 2010/4
N2 - Vaginal melanoma (VM) is a rare disease comprising, 1% of all melanomas among women, and about 3% of all vaginal malignancies. Patients experience a poor prognosis, showing, 15% 5-year survival. The report concerns two premenopausal patients with VM treated by surgery with radical intent. The first patient presented with a large lesion also infiltrating the proximal paracolpium and the bladder. The second patient had a persistent lesion of the lower third of the vagina. However, in the absence of any evidence-based guidelines or even clear suggestions from the literature, it is reasonable to believe that an appropriate management of primary malignant VM should address the radical tumor resection with wide tumor-free surgical margins and symptom relief.
AB - Vaginal melanoma (VM) is a rare disease comprising, 1% of all melanomas among women, and about 3% of all vaginal malignancies. Patients experience a poor prognosis, showing, 15% 5-year survival. The report concerns two premenopausal patients with VM treated by surgery with radical intent. The first patient presented with a large lesion also infiltrating the proximal paracolpium and the bladder. The second patient had a persistent lesion of the lower third of the vagina. However, in the absence of any evidence-based guidelines or even clear suggestions from the literature, it is reasonable to believe that an appropriate management of primary malignant VM should address the radical tumor resection with wide tumor-free surgical margins and symptom relief.
KW - Gynecological cancer
KW - Vaginal malignancies
KW - Vaginal melanoma
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M3 - Article
C2 - 20718317
AN - SCOPUS:77956630527
VL - 95
SP - 120
EP - 125
JO - International Surgery
JF - International Surgery
SN - 0020-8868
IS - 2
ER -