Malignant melanoma of the vagina: Report of two cases and review of the literature

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5 Citations (Scopus)

Abstract

Vaginal melanoma (VM) is a rare disease comprising, 1% of all melanomas among women, and about 3% of all vaginal malignancies. Patients experience a poor prognosis, showing, 15% 5-year survival. The report concerns two premenopausal patients with VM treated by surgery with radical intent. The first patient presented with a large lesion also infiltrating the proximal paracolpium and the bladder. The second patient had a persistent lesion of the lower third of the vagina. However, in the absence of any evidence-based guidelines or even clear suggestions from the literature, it is reasonable to believe that an appropriate management of primary malignant VM should address the radical tumor resection with wide tumor-free surgical margins and symptom relief.

Original languageEnglish
Pages (from-to)120-125
Number of pages6
JournalInternational Surgery
Volume95
Issue number2
Publication statusPublished - Apr 2010

Fingerprint

Vagina
Melanoma
Rare Diseases
Neoplasms
Urinary Bladder
Guidelines
Survival
Margins of Excision

Keywords

  • Gynecological cancer
  • Vaginal malignancies
  • Vaginal melanoma

ASJC Scopus subject areas

  • Surgery

Cite this

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title = "Malignant melanoma of the vagina: Report of two cases and review of the literature",
abstract = "Vaginal melanoma (VM) is a rare disease comprising, 1{\%} of all melanomas among women, and about 3{\%} of all vaginal malignancies. Patients experience a poor prognosis, showing, 15{\%} 5-year survival. The report concerns two premenopausal patients with VM treated by surgery with radical intent. The first patient presented with a large lesion also infiltrating the proximal paracolpium and the bladder. The second patient had a persistent lesion of the lower third of the vagina. However, in the absence of any evidence-based guidelines or even clear suggestions from the literature, it is reasonable to believe that an appropriate management of primary malignant VM should address the radical tumor resection with wide tumor-free surgical margins and symptom relief.",
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T1 - Malignant melanoma of the vagina

T2 - Report of two cases and review of the literature

AU - Greggi, Stefano

AU - Losito, Simona

AU - Pisano, Carmela

AU - Desicato, Sonia

AU - Scaffa, Cono

PY - 2010/4

Y1 - 2010/4

N2 - Vaginal melanoma (VM) is a rare disease comprising, 1% of all melanomas among women, and about 3% of all vaginal malignancies. Patients experience a poor prognosis, showing, 15% 5-year survival. The report concerns two premenopausal patients with VM treated by surgery with radical intent. The first patient presented with a large lesion also infiltrating the proximal paracolpium and the bladder. The second patient had a persistent lesion of the lower third of the vagina. However, in the absence of any evidence-based guidelines or even clear suggestions from the literature, it is reasonable to believe that an appropriate management of primary malignant VM should address the radical tumor resection with wide tumor-free surgical margins and symptom relief.

AB - Vaginal melanoma (VM) is a rare disease comprising, 1% of all melanomas among women, and about 3% of all vaginal malignancies. Patients experience a poor prognosis, showing, 15% 5-year survival. The report concerns two premenopausal patients with VM treated by surgery with radical intent. The first patient presented with a large lesion also infiltrating the proximal paracolpium and the bladder. The second patient had a persistent lesion of the lower third of the vagina. However, in the absence of any evidence-based guidelines or even clear suggestions from the literature, it is reasonable to believe that an appropriate management of primary malignant VM should address the radical tumor resection with wide tumor-free surgical margins and symptom relief.

KW - Gynecological cancer

KW - Vaginal malignancies

KW - Vaginal melanoma

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