Malignant neuroblastic tumors in adolescents

Massimo Conte, Bruno De Bernardi, Claudia Milanaccio, Alberto Michelazzi, Antonino Rizzo, Giovanni Montobbio, Stefano Parodi, Riccardo Haupt

Research output: Contribution to journalArticle

Abstract

Malignant neuroblastic tumors (MNT) commonly affect children in the early years of life and become rare afterwards. The clinical characteristics and outcome of these tumors occurring in adolescents are still unclear. In this review, the main clinical reports available in the literature are summarized together with some original data. In general, MNT occurring in adolescents, if compared to those occurring in children, are more frequently diagnosed in advanced stages, have uncommon sites of metastases, but have less frequently unfavorable biological markers. If treated with standard protocols as those used for children, their survival is poor; in particular, patients with localized disease seem to have a more aggressive course than children.

Original languageEnglish
Pages (from-to)271-274
Number of pages4
JournalCancer Letters
Volume228
Issue number1-2
DOIs
Publication statusPublished - Oct 18 2005

    Fingerprint

Keywords

  • Adolescents
  • Malignant neuroblastic tumors
  • Neuroblastoma

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Biology
  • Oncology

Cite this