Malignant pleural mesothelioma: Multivariate analysis of prognostic factors on 113 patients

V. Fusco, A. Ardizzoni, F. Merlo, A. Cinquegrana, B. Faravelli, M. De Palma, L. Chessa, G. Nicolo, M. Serra, A. Capaccio, R. Rosso

Research output: Contribution to journalArticlepeer-review

Abstract

We report on clinical features of 113 cases of pathologically confirmed Malignant Pleural Mesothelioma, observed in Genoa (Italy) between 1979 and 1985. Overall median survival was 10 months. Among the pretreatment variables studied (age, sex, asbestos exposure, pathological type, chest pain and dyspnea et the time of diagnosis), the only one of prognostic value in the univariate analysis was the histological subtype: median survivals were l2, 7 and 4 months for the patients in the epithelial, mixed, and fibrosarcomatous groups, respectively (p = 0.0012). A multivariate analysis confirmed the independent predictive power of the histotype (p = 0.0022). A review of literature data concerning prognostic factors in Malignant Pleural Mesothelioma is presented.

Original languageEnglish
Pages (from-to)683-689
Number of pages7
JournalAnticancer Research
Volume13
Issue number3
Publication statusPublished - 1993

Keywords

  • Mesothelioma
  • Multivariate analysis
  • Pleural diseases
  • Prognostic factors

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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