Malignant sarcomatoid mesothelioma of the pleura

a histological and immunohistological study of a case.

C. Avellini, G. Alampi, V. Cocchi, E. Sabattini, R. Agosti, M. Schiavina, S. Pileri, A. Piccaluga

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The authors describe the case of a 70 year-old asymptomatic female, who showed nodular pleural growths at an occasional chest roentgenogram. Histological examinations and laboratory findings excluded the possibility of an inflammatory granulomatous process, but they did not allow differentiation between malignant sarcomatoid pleural mesothelioma and malignant fibrous histiocytoma. Only at immunohistochemistry was the differential diagnosis made. In fact, the co-expression of vimentin and cytokeratins by neoplastic cells, along with their negativity for macrophage markers strongly supported the hypothesis that the neoplastic growth originated from subpleural mesenchymal stem cells.

Original languageEnglish
Pages (from-to)335-340
Number of pages6
JournalPathologica
Volume83
Issue number1085
Publication statusPublished - May 1991

Fingerprint

Pleura
Malignant Fibrous Histiocytoma
Mesothelioma
Vimentin
Growth
Keratins
Mesenchymal Stromal Cells
Differential Diagnosis
Thorax
Immunohistochemistry
Macrophages
Malignant Mesothelioma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Avellini, C., Alampi, G., Cocchi, V., Sabattini, E., Agosti, R., Schiavina, M., ... Piccaluga, A. (1991). Malignant sarcomatoid mesothelioma of the pleura: a histological and immunohistological study of a case. Pathologica, 83(1085), 335-340.

Malignant sarcomatoid mesothelioma of the pleura : a histological and immunohistological study of a case. / Avellini, C.; Alampi, G.; Cocchi, V.; Sabattini, E.; Agosti, R.; Schiavina, M.; Pileri, S.; Piccaluga, A.

In: Pathologica, Vol. 83, No. 1085, 05.1991, p. 335-340.

Research output: Contribution to journalArticle

Avellini, C, Alampi, G, Cocchi, V, Sabattini, E, Agosti, R, Schiavina, M, Pileri, S & Piccaluga, A 1991, 'Malignant sarcomatoid mesothelioma of the pleura: a histological and immunohistological study of a case.', Pathologica, vol. 83, no. 1085, pp. 335-340.
Avellini C, Alampi G, Cocchi V, Sabattini E, Agosti R, Schiavina M et al. Malignant sarcomatoid mesothelioma of the pleura: a histological and immunohistological study of a case. Pathologica. 1991 May;83(1085):335-340.
Avellini, C. ; Alampi, G. ; Cocchi, V. ; Sabattini, E. ; Agosti, R. ; Schiavina, M. ; Pileri, S. ; Piccaluga, A. / Malignant sarcomatoid mesothelioma of the pleura : a histological and immunohistological study of a case. In: Pathologica. 1991 ; Vol. 83, No. 1085. pp. 335-340.
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