Malignant transformation of ectopic pancreatic cells in the duodenal wall

Roberto Bini, Paolo Voghera, Alberto Tapparo, Raffaele Nunziata, Andrea Demarchi, Matteo Capocefalo, Renzo Leli

Research output: Contribution to journalArticlepeer-review


Ectopic pancreas (EP) is the relatively uncommon presence of pancreatic tissue outside the normal location of the pancreas. This condition is usually asymptomatic and rarely complicated by pancreatitis and malignant transformation. A few cases of neoplastic phenomena that developed from EP into the duodenal wall are described in the literature. Herein we report a case of gastric outlet obstruction due to adenocarcinoma arising from EP of the duodenal wall. The patient underwent a Whipple's procedure and had an uneventful post-operative recovery. Traditional imaging studies are often inconclusive in the definitive diagnosis, whilst endoscopic ultrasonography and guided biopsy may aid accurate pre-operative diagnosis. Diagnostic uncertainty warrants surgical exploration and if necessary extended resection is indicated.

Original languageEnglish
Pages (from-to)1293-1295
Number of pages3
JournalWorld Journal of Gastroenterology
Issue number10
Publication statusPublished - 2010


  • Duodenum
  • Ectopic pancreas
  • Gastrointestinal obstruction
  • Neoplasm
  • Pancreaticoduodenectomy

ASJC Scopus subject areas

  • Gastroenterology


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