TY - JOUR
T1 - Malignant transformation of ectopic pancreatic cells in the duodenal wall
AU - Bini, Roberto
AU - Voghera, Paolo
AU - Tapparo, Alberto
AU - Nunziata, Raffaele
AU - Demarchi, Andrea
AU - Capocefalo, Matteo
AU - Leli, Renzo
PY - 2010
Y1 - 2010
N2 - Ectopic pancreas (EP) is the relatively uncommon presence of pancreatic tissue outside the normal location of the pancreas. This condition is usually asymptomatic and rarely complicated by pancreatitis and malignant transformation. A few cases of neoplastic phenomena that developed from EP into the duodenal wall are described in the literature. Herein we report a case of gastric outlet obstruction due to adenocarcinoma arising from EP of the duodenal wall. The patient underwent a Whipple's procedure and had an uneventful post-operative recovery. Traditional imaging studies are often inconclusive in the definitive diagnosis, whilst endoscopic ultrasonography and guided biopsy may aid accurate pre-operative diagnosis. Diagnostic uncertainty warrants surgical exploration and if necessary extended resection is indicated.
AB - Ectopic pancreas (EP) is the relatively uncommon presence of pancreatic tissue outside the normal location of the pancreas. This condition is usually asymptomatic and rarely complicated by pancreatitis and malignant transformation. A few cases of neoplastic phenomena that developed from EP into the duodenal wall are described in the literature. Herein we report a case of gastric outlet obstruction due to adenocarcinoma arising from EP of the duodenal wall. The patient underwent a Whipple's procedure and had an uneventful post-operative recovery. Traditional imaging studies are often inconclusive in the definitive diagnosis, whilst endoscopic ultrasonography and guided biopsy may aid accurate pre-operative diagnosis. Diagnostic uncertainty warrants surgical exploration and if necessary extended resection is indicated.
KW - Duodenum
KW - Ectopic pancreas
KW - Gastrointestinal obstruction
KW - Neoplasm
KW - Pancreaticoduodenectomy
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U2 - 10.3748/wjg.v16.i10.1293
DO - 10.3748/wjg.v16.i10.1293
M3 - Article
C2 - 20222176
AN - SCOPUS:77950159482
VL - 16
SP - 1293
EP - 1295
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
IS - 10
ER -