Abstract
Full-length cDNA clones have been isolated encoding purified augmenter of liver regeneration (ALR) polypeptides prepared from the cytosol of livers from weanling rats and from humans. The full-length clone from the rat is a 1226 bp cDNA containing an 81 bp 5′-untranslated region, a 594 bp coding region and a 551 bp 3′-untranslated region. The coding region encodes three proteins with estimated molecular weights of 15,081, 20,193 and 22,835. The full-length clone from the human consists of a 727 bp cDNA containing a 4 bp 5′-untranslated region, a 615 bp coding region and a 108 bp 3′-untranslated region, including the termination codon TAG and the poly (A) region. The 615 bp coding region encodes four proteins, human ALR-V1, ALR-V2, ALR-V3 and ALR, having estimated molecular weights of 23,448, 20,834, 20,703 and 15,028, respectively.
| Original language | English |
|---|---|
| Pages (from-to) | 678 |
| Number of pages | 1 |
| Journal | Biotechnology Advances |
| Volume | 15 |
| Issue number | 3-4 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Biotechnology
Cite this
Mammalian augmenter of liver regeneration and variants thereof. / Francavilla, Antonio T.; Hagiya, Michio; Starzl, Thomas E.
In: Biotechnology Advances, Vol. 15, No. 3-4, 1997, p. 678.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mammalian augmenter of liver regeneration and variants thereof
AU - Francavilla, Antonio T.
AU - Hagiya, Michio
AU - Starzl, Thomas E.
PY - 1997
Y1 - 1997
N2 - Full-length cDNA clones have been isolated encoding purified augmenter of liver regeneration (ALR) polypeptides prepared from the cytosol of livers from weanling rats and from humans. The full-length clone from the rat is a 1226 bp cDNA containing an 81 bp 5′-untranslated region, a 594 bp coding region and a 551 bp 3′-untranslated region. The coding region encodes three proteins with estimated molecular weights of 15,081, 20,193 and 22,835. The full-length clone from the human consists of a 727 bp cDNA containing a 4 bp 5′-untranslated region, a 615 bp coding region and a 108 bp 3′-untranslated region, including the termination codon TAG and the poly (A) region. The 615 bp coding region encodes four proteins, human ALR-V1, ALR-V2, ALR-V3 and ALR, having estimated molecular weights of 23,448, 20,834, 20,703 and 15,028, respectively.
AB - Full-length cDNA clones have been isolated encoding purified augmenter of liver regeneration (ALR) polypeptides prepared from the cytosol of livers from weanling rats and from humans. The full-length clone from the rat is a 1226 bp cDNA containing an 81 bp 5′-untranslated region, a 594 bp coding region and a 551 bp 3′-untranslated region. The coding region encodes three proteins with estimated molecular weights of 15,081, 20,193 and 22,835. The full-length clone from the human consists of a 727 bp cDNA containing a 4 bp 5′-untranslated region, a 615 bp coding region and a 108 bp 3′-untranslated region, including the termination codon TAG and the poly (A) region. The 615 bp coding region encodes four proteins, human ALR-V1, ALR-V2, ALR-V3 and ALR, having estimated molecular weights of 23,448, 20,834, 20,703 and 15,028, respectively.
UR - http://www.scopus.com/inward/record.url?scp=0030721901&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030721901&partnerID=8YFLogxK
M3 - Article
VL - 15
SP - 678
JO - Biotechnology Advances
JF - Biotechnology Advances
SN - 0734-9750
IS - 3-4
ER -