Mammary carcinoma with argyrophilic cells: An immunohistochemical and ultrastructural study

D. Santini, F. Bazzocchi, S. Pileri, E. Govoni, M. Taffurelli, A. Grassigli, D. Marrano, G. Martinelli

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The immunohistochemical and ultrastructural findings of 7 primary argyrophilic tumors of the breast are described. Five cases were selected because of a growth pattern reminiscent of a 'carcinoid' tumor and 2 were obtained from 70 consecutive common carcinomas. All patients were females (mean age 68.8) and none had clinical evidence of hormonal secretion. On ultrastructural examination dense-core granules were seen in addition to findings more suggestive of a common carcinoma. Immunoperoxidase stainings for ACTH, calcitonin etc. were negative in all tumors. The authors believe that organoid growth pattern, argyrophilia and dense-core neurosecretory-like granules are not sufficient elements to demonstrate the endocrine nature of a breast neoplasm.

Original languageEnglish
Pages (from-to)331-338
Number of pages8
JournalTumori
Volume71
Issue number4
Publication statusPublished - 1985

Fingerprint

Organoids
Breast Neoplasms
Carcinoma
Carcinoid Tumor
Calcitonin
Growth
Adrenocorticotropic Hormone
Staining and Labeling
Neoplasms

ASJC Scopus subject areas

  • Cancer Research

Cite this

Santini, D., Bazzocchi, F., Pileri, S., Govoni, E., Taffurelli, M., Grassigli, A., ... Martinelli, G. (1985). Mammary carcinoma with argyrophilic cells: An immunohistochemical and ultrastructural study. Tumori, 71(4), 331-338.

Mammary carcinoma with argyrophilic cells : An immunohistochemical and ultrastructural study. / Santini, D.; Bazzocchi, F.; Pileri, S.; Govoni, E.; Taffurelli, M.; Grassigli, A.; Marrano, D.; Martinelli, G.

In: Tumori, Vol. 71, No. 4, 1985, p. 331-338.

Research output: Contribution to journalArticle

Santini, D, Bazzocchi, F, Pileri, S, Govoni, E, Taffurelli, M, Grassigli, A, Marrano, D & Martinelli, G 1985, 'Mammary carcinoma with argyrophilic cells: An immunohistochemical and ultrastructural study', Tumori, vol. 71, no. 4, pp. 331-338.
Santini D, Bazzocchi F, Pileri S, Govoni E, Taffurelli M, Grassigli A et al. Mammary carcinoma with argyrophilic cells: An immunohistochemical and ultrastructural study. Tumori. 1985;71(4):331-338.
Santini, D. ; Bazzocchi, F. ; Pileri, S. ; Govoni, E. ; Taffurelli, M. ; Grassigli, A. ; Marrano, D. ; Martinelli, G. / Mammary carcinoma with argyrophilic cells : An immunohistochemical and ultrastructural study. In: Tumori. 1985 ; Vol. 71, No. 4. pp. 331-338.
@article{ce51c39470d04055928e534502919d54,
title = "Mammary carcinoma with argyrophilic cells: An immunohistochemical and ultrastructural study",
abstract = "The immunohistochemical and ultrastructural findings of 7 primary argyrophilic tumors of the breast are described. Five cases were selected because of a growth pattern reminiscent of a 'carcinoid' tumor and 2 were obtained from 70 consecutive common carcinomas. All patients were females (mean age 68.8) and none had clinical evidence of hormonal secretion. On ultrastructural examination dense-core granules were seen in addition to findings more suggestive of a common carcinoma. Immunoperoxidase stainings for ACTH, calcitonin etc. were negative in all tumors. The authors believe that organoid growth pattern, argyrophilia and dense-core neurosecretory-like granules are not sufficient elements to demonstrate the endocrine nature of a breast neoplasm.",
author = "D. Santini and F. Bazzocchi and S. Pileri and E. Govoni and M. Taffurelli and A. Grassigli and D. Marrano and G. Martinelli",
year = "1985",
language = "English",
volume = "71",
pages = "331--338",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "4",

}

TY - JOUR

T1 - Mammary carcinoma with argyrophilic cells

T2 - An immunohistochemical and ultrastructural study

AU - Santini, D.

AU - Bazzocchi, F.

AU - Pileri, S.

AU - Govoni, E.

AU - Taffurelli, M.

AU - Grassigli, A.

AU - Marrano, D.

AU - Martinelli, G.

PY - 1985

Y1 - 1985

N2 - The immunohistochemical and ultrastructural findings of 7 primary argyrophilic tumors of the breast are described. Five cases were selected because of a growth pattern reminiscent of a 'carcinoid' tumor and 2 were obtained from 70 consecutive common carcinomas. All patients were females (mean age 68.8) and none had clinical evidence of hormonal secretion. On ultrastructural examination dense-core granules were seen in addition to findings more suggestive of a common carcinoma. Immunoperoxidase stainings for ACTH, calcitonin etc. were negative in all tumors. The authors believe that organoid growth pattern, argyrophilia and dense-core neurosecretory-like granules are not sufficient elements to demonstrate the endocrine nature of a breast neoplasm.

AB - The immunohistochemical and ultrastructural findings of 7 primary argyrophilic tumors of the breast are described. Five cases were selected because of a growth pattern reminiscent of a 'carcinoid' tumor and 2 were obtained from 70 consecutive common carcinomas. All patients were females (mean age 68.8) and none had clinical evidence of hormonal secretion. On ultrastructural examination dense-core granules were seen in addition to findings more suggestive of a common carcinoma. Immunoperoxidase stainings for ACTH, calcitonin etc. were negative in all tumors. The authors believe that organoid growth pattern, argyrophilia and dense-core neurosecretory-like granules are not sufficient elements to demonstrate the endocrine nature of a breast neoplasm.

UR - http://www.scopus.com/inward/record.url?scp=0022363380&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022363380&partnerID=8YFLogxK

M3 - Article

C2 - 2413598

AN - SCOPUS:0022363380

VL - 71

SP - 331

EP - 338

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 4

ER -