Management of Acute and Recurrent Pericarditis: JACC State-of-the-Art Review

Juan Guido Chiabrando, Aldo Bonaventura, Alessandra Vecchié, George F. Wohlford, Adolfo G. Mauro, Jennifer H. Jordan, John D. Grizzard, Fabrizio Montecucco, Daniel Horacio Berrocal, Antonio Brucato, Massimo Imazio, Antonio Abbate

Research output: Contribution to journalReview article

Abstract

Pericarditis refers to the inflammation of the pericardial layers, resulting from a variety of stimuli triggering a stereotyped immune response, and characterized by chest pain associated often with peculiar electrocardiographic changes and, at times, accompanied by pericardial effusion. Acute pericarditis is generally self-limited and not life-threatening; yet, it may cause significant short-term disability, be complicated by either a large pericardial effusion or tamponade, and carry a significant risk of recurrence. The mainstay of treatment of pericarditis is represented by anti-inflammatory drugs. Anti-inflammatory treatments vary, however, in both effectiveness and side-effect profile. The objective of this review is to summarize the up-to-date management of acute and recurrent pericarditis.

Original languageEnglish
Pages (from-to)76-92
Number of pages17
JournalJournal of the American College of Cardiology
Volume75
Issue number1
DOIs
Publication statusPublished - Jan 7 2020

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Keywords

  • acute pericarditis
  • cardiac tamponade
  • constrictive pericarditis
  • recurrent pericarditis
  • treatment

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Chiabrando, J. G., Bonaventura, A., Vecchié, A., Wohlford, G. F., Mauro, A. G., Jordan, J. H., Grizzard, J. D., Montecucco, F., Berrocal, D. H., Brucato, A., Imazio, M., & Abbate, A. (2020). Management of Acute and Recurrent Pericarditis: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 75(1), 76-92. https://doi.org/10.1016/j.jacc.2019.11.021