Breast cancer is the most common malignancy in women, with a worldwide prevalence of 1.5 million throughout industrialized countries. Metastases from cancer are the most common form of malignancy involving the bone, with the highest prevalence in breast, prostate and lung cancer. Advances made in the diagnosis and treatment of tumors (e.g., surgery, chemotherapy, biotherapy and radiotherapy) have increased survival in cancer patients over the last 20 years. The presence of osteosclerosis as the predominant form of metastasis is associated with improved survival in BM breast cancer patients. Another important factor that influences survival is the presence of solitary or multiple metastatic skeletal lesions. Imaging of bone metastases in breast cancer is an essential step to staging, planning treatment, and monitoring the response to treatment. Current treatment of metastatic breast cancer aims to achieve meaningful clinical responses, improved quality of life, long-term remissions and prolonged survival.
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