Management of bone metastases in breast cancer

Toni Ibrahim, Dino Amadori

Research output: Chapter in Book/Report/Conference proceedingChapter


Breast cancer is the most common malignancy in women, with a worldwide prevalence of 1.5 million throughout industrialized countries. Metastases from cancer are the most common form of malignancy involving the bone, with the highest prevalence in breast, prostate and lung cancer. Advances made in the diagnosis and treatment of tumors (e.g., surgery, chemotherapy, biotherapy and radiotherapy) have increased survival in cancer patients over the last 20 years. The presence of osteosclerosis as the predominant form of metastasis is associated with improved survival in BM breast cancer patients. Another important factor that influences survival is the presence of solitary or multiple metastatic skeletal lesions. Imaging of bone metastases in breast cancer is an essential step to staging, planning treatment, and monitoring the response to treatment. Current treatment of metastatic breast cancer aims to achieve meaningful clinical responses, improved quality of life, long-term remissions and prolonged survival.

Original languageEnglish
Title of host publicationAdvances in Bone Metastasis Management
PublisherFuture Medicine Ltd.
Number of pages12
ISBN (Print)9781780840307, 9781780841151
Publication statusPublished - Mar 1 2012


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ibrahim, T., & Amadori, D. (2012). Management of bone metastases in breast cancer. In Advances in Bone Metastasis Management (pp. 45-56). Future Medicine Ltd..