Management of metastatic retroperitoneal sarcoma: a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG)

Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG), Andrea J. MacNeill, Winan J van Houdt, Carol J. Swallow, Alessandro Gronchi

Research output: Contribution to journalArticle

Abstract

Introduction: Retroperitoneal sarcoma (RPS) is a rare disease accounting for 0.1%-0.2% of all malignancies. Management of RPS is complex and requires multidisciplinary, tailored treatment strategies at all stages, but especially in the context of metastatic or multifocal recurrent disease. Due to the rarity and heterogeneity of this family of diseases, the literature to guide management is limited.

Methods: The Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG) is an international collaboration of sarcoma experts from all disciplines convened in an effort to overcome these limitations. The TARPSWG has compiled the available evidence surrounding metastatic and multifocally recurrent RPS along with expert opinion in an iterative process to generate a consensus document regarding the complex management of this disease. The objective of this document is to guide sarcoma specialists from all disciplines in the diagnosis and treatment of multifocal recurrent or metastatic RPS.

Results: All aspects of patient assessment, diagnostic processes, local and systemic treatments, and palliation are reviewed in this document, and consensus recommendations provided accordingly. Recommendations were guided by available evidence, in conjunction with expert opinion where evidence was lacking.

Conclusions: This consensus document combines the available literature regarding the management of multifocally recurrent or metastastic RPS with the practical expertise of high-volume sarcoma centers from multiple countries. It is designed as a tool for decision making in the complex multidisciplinary management of this condition and is expected to standardize management across centers, thereby ensuring that patients receive the highest quality care.

Original languageEnglish
Pages (from-to)857-871
Number of pages15
JournalAnnals of oncology : official journal of the European Society for Medical Oncology
Volume29
Issue number4
DOIs
Publication statusPublished - Apr 1 2018

Fingerprint

Sarcoma
Consensus
Expert Testimony
Process Assessment (Health Care)
Quality of Health Care
Disease Management
Rare Diseases
Decision Making
Therapeutics

Cite this

Management of metastatic retroperitoneal sarcoma : a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG). / Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG); MacNeill, Andrea J.; van Houdt, Winan J; Swallow, Carol J.; Gronchi, Alessandro.

In: Annals of oncology : official journal of the European Society for Medical Oncology, Vol. 29, No. 4, 01.04.2018, p. 857-871.

Research output: Contribution to journalArticle

Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG) ; MacNeill, Andrea J. ; van Houdt, Winan J ; Swallow, Carol J. ; Gronchi, Alessandro. / Management of metastatic retroperitoneal sarcoma : a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG). In: Annals of oncology : official journal of the European Society for Medical Oncology. 2018 ; Vol. 29, No. 4. pp. 857-871.
@article{7acef889419f494fb3921ae9f5592bb8,
title = "Management of metastatic retroperitoneal sarcoma: a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG)",
abstract = "Introduction: Retroperitoneal sarcoma (RPS) is a rare disease accounting for 0.1{\%}-0.2{\%} of all malignancies. Management of RPS is complex and requires multidisciplinary, tailored treatment strategies at all stages, but especially in the context of metastatic or multifocal recurrent disease. Due to the rarity and heterogeneity of this family of diseases, the literature to guide management is limited.Methods: The Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG) is an international collaboration of sarcoma experts from all disciplines convened in an effort to overcome these limitations. The TARPSWG has compiled the available evidence surrounding metastatic and multifocally recurrent RPS along with expert opinion in an iterative process to generate a consensus document regarding the complex management of this disease. The objective of this document is to guide sarcoma specialists from all disciplines in the diagnosis and treatment of multifocal recurrent or metastatic RPS.Results: All aspects of patient assessment, diagnostic processes, local and systemic treatments, and palliation are reviewed in this document, and consensus recommendations provided accordingly. Recommendations were guided by available evidence, in conjunction with expert opinion where evidence was lacking.Conclusions: This consensus document combines the available literature regarding the management of multifocally recurrent or metastastic RPS with the practical expertise of high-volume sarcoma centers from multiple countries. It is designed as a tool for decision making in the complex multidisciplinary management of this condition and is expected to standardize management across centers, thereby ensuring that patients receive the highest quality care.",
author = "{Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG)} and MacNeill, {Andrea J.} and {van Houdt}, {Winan J} and Swallow, {Carol J.} and Alessandro Gronchi",
year = "2018",
month = "4",
day = "1",
doi = "10.1093/annonc/mdy052",
language = "English",
volume = "29",
pages = "857--871",
journal = "Annals of Oncology",
issn = "0923-7534",
publisher = "NLM (Medline)",
number = "4",

}

TY - JOUR

T1 - Management of metastatic retroperitoneal sarcoma

T2 - a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG)

AU - Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG)

AU - MacNeill, Andrea J.

AU - van Houdt, Winan J

AU - Swallow, Carol J.

AU - Gronchi, Alessandro

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Introduction: Retroperitoneal sarcoma (RPS) is a rare disease accounting for 0.1%-0.2% of all malignancies. Management of RPS is complex and requires multidisciplinary, tailored treatment strategies at all stages, but especially in the context of metastatic or multifocal recurrent disease. Due to the rarity and heterogeneity of this family of diseases, the literature to guide management is limited.Methods: The Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG) is an international collaboration of sarcoma experts from all disciplines convened in an effort to overcome these limitations. The TARPSWG has compiled the available evidence surrounding metastatic and multifocally recurrent RPS along with expert opinion in an iterative process to generate a consensus document regarding the complex management of this disease. The objective of this document is to guide sarcoma specialists from all disciplines in the diagnosis and treatment of multifocal recurrent or metastatic RPS.Results: All aspects of patient assessment, diagnostic processes, local and systemic treatments, and palliation are reviewed in this document, and consensus recommendations provided accordingly. Recommendations were guided by available evidence, in conjunction with expert opinion where evidence was lacking.Conclusions: This consensus document combines the available literature regarding the management of multifocally recurrent or metastastic RPS with the practical expertise of high-volume sarcoma centers from multiple countries. It is designed as a tool for decision making in the complex multidisciplinary management of this condition and is expected to standardize management across centers, thereby ensuring that patients receive the highest quality care.

AB - Introduction: Retroperitoneal sarcoma (RPS) is a rare disease accounting for 0.1%-0.2% of all malignancies. Management of RPS is complex and requires multidisciplinary, tailored treatment strategies at all stages, but especially in the context of metastatic or multifocal recurrent disease. Due to the rarity and heterogeneity of this family of diseases, the literature to guide management is limited.Methods: The Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG) is an international collaboration of sarcoma experts from all disciplines convened in an effort to overcome these limitations. The TARPSWG has compiled the available evidence surrounding metastatic and multifocally recurrent RPS along with expert opinion in an iterative process to generate a consensus document regarding the complex management of this disease. The objective of this document is to guide sarcoma specialists from all disciplines in the diagnosis and treatment of multifocal recurrent or metastatic RPS.Results: All aspects of patient assessment, diagnostic processes, local and systemic treatments, and palliation are reviewed in this document, and consensus recommendations provided accordingly. Recommendations were guided by available evidence, in conjunction with expert opinion where evidence was lacking.Conclusions: This consensus document combines the available literature regarding the management of multifocally recurrent or metastastic RPS with the practical expertise of high-volume sarcoma centers from multiple countries. It is designed as a tool for decision making in the complex multidisciplinary management of this condition and is expected to standardize management across centers, thereby ensuring that patients receive the highest quality care.

U2 - 10.1093/annonc/mdy052

DO - 10.1093/annonc/mdy052

M3 - Article

C2 - 29432564

VL - 29

SP - 857

EP - 871

JO - Annals of Oncology

JF - Annals of Oncology

SN - 0923-7534

IS - 4

ER -