TY - JOUR
T1 - Management of oral drug therapy in elderly patients with dysphagia
AU - Fusco, Sergio
AU - Cariati, D.
AU - Schepisi, R.
AU - Ganzetti, Roberta
AU - Sestili, Matteo
AU - David, S.
AU - Ferrara, L.
AU - Liuzzi Gatto, M.
AU - Vena, S.
AU - Corsonello, A.
AU - Corica, F.
PY - 2016
Y1 - 2016
N2 - We aimed at summarizing current evidence on age-related changes in swallowing, the impact of selected medications on swallowing, and the management of oral drug therapy in older patients with dysphagia. The risk for oropharyngeal swallowing disorders increases with age. Though increasing age facilitates subtle physiologic changes in swallow function, age-related diseases are most significant factors in the onset and severity of dysphagia. In older people, dysphagia can also occur as a side effect of some medications. Drug-induced dysphagia can appear as a drug side effect or as a complication of the therapeutic action of the drug, mainly through induction of xerostomia, impaired swallowing muscle function or esophageal injury. Whatever the mechanism leading to dysphagia, the administraton of drugs to dysphagic patients is a really challenging issue. Manipulations of solid oral drugs frequently occur in geriatric settings, leading to potential medication errors and changes in drug performance. The implementation of guidelines for management of oral drug therapy in dysphagic patients may contribute to improve the quality of care provided to this very frail population.
AB - We aimed at summarizing current evidence on age-related changes in swallowing, the impact of selected medications on swallowing, and the management of oral drug therapy in older patients with dysphagia. The risk for oropharyngeal swallowing disorders increases with age. Though increasing age facilitates subtle physiologic changes in swallow function, age-related diseases are most significant factors in the onset and severity of dysphagia. In older people, dysphagia can also occur as a side effect of some medications. Drug-induced dysphagia can appear as a drug side effect or as a complication of the therapeutic action of the drug, mainly through induction of xerostomia, impaired swallowing muscle function or esophageal injury. Whatever the mechanism leading to dysphagia, the administraton of drugs to dysphagic patients is a really challenging issue. Manipulations of solid oral drugs frequently occur in geriatric settings, leading to potential medication errors and changes in drug performance. The implementation of guidelines for management of oral drug therapy in dysphagic patients may contribute to improve the quality of care provided to this very frail population.
KW - Dysphagia
KW - Elderly
KW - Functional status
KW - Medication-induced dysphagia
KW - Polypharmacy
KW - Swallowing disorders
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M3 - Review article
AN - SCOPUS:84983486402
VL - 64
SP - 9
JO - Journal of Gerontology and Geriatrics
JF - Journal of Gerontology and Geriatrics
SN - 2499-6564
IS - 1
ER -