TY - JOUR
T1 - Management of thyroid follicular proliferation
T2 - An ultrasound-based malignancy score to opt for surgical or conservative treatment
AU - Pompili, Giovanni
AU - Tresoldi, Silvia
AU - Primolevo, Alessandra
AU - De Pasquale, Loredana
AU - Di Leo, Giovanni
AU - Cornalba, Gianpaolo
PY - 2013/8
Y1 - 2013/8
N2 - This study was conducted to evaluate whether ultrasound characteristics of thyroid nodules with a known cytologic diagnosis of "follicular pattern" (indicative of follicular hyperplasia, follicular adenoma or follicular carcinoma) can be used to define a nodule malignancy score to limit surgery to selected, higher-risk cases. In pre-operative ultrasound results of patients diagnosed with a "follicular pattern" on cytology who subsequently underwent surgery, each nodule feature was given a score from 0 (most likely benign) to 2 (most likely malignant), resulting in a total score ranging from 0 to 11. The total nodule score (total malignancy score) was then compared with the definitive histologic diagnosis. According to our results, surgery is advisable in patients with score≥4(79% of carcinomas), ultrasound follow-up seems to be appropriate for patients with a score of 3 (21% of carcinomas) and no action is recommended for patients with score
AB - This study was conducted to evaluate whether ultrasound characteristics of thyroid nodules with a known cytologic diagnosis of "follicular pattern" (indicative of follicular hyperplasia, follicular adenoma or follicular carcinoma) can be used to define a nodule malignancy score to limit surgery to selected, higher-risk cases. In pre-operative ultrasound results of patients diagnosed with a "follicular pattern" on cytology who subsequently underwent surgery, each nodule feature was given a score from 0 (most likely benign) to 2 (most likely malignant), resulting in a total score ranging from 0 to 11. The total nodule score (total malignancy score) was then compared with the definitive histologic diagnosis. According to our results, surgery is advisable in patients with score≥4(79% of carcinomas), ultrasound follow-up seems to be appropriate for patients with a score of 3 (21% of carcinomas) and no action is recommended for patients with score
KW - Cytodiagnosis
KW - Diagnostic imaging
KW - Fine-needle biopsy
KW - Follicular thyroid carcinoma
KW - Thyroid nodule
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=84880041405&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880041405&partnerID=8YFLogxK
U2 - 10.1016/j.ultrasmedbio.2013.02.464
DO - 10.1016/j.ultrasmedbio.2013.02.464
M3 - Article
C2 - 23743097
AN - SCOPUS:84880041405
VL - 39
SP - 1350
EP - 1355
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
SN - 0301-5629
IS - 8
ER -