Management of thyroid follicular proliferation: An ultrasound-based malignancy score to opt for surgical or conservative treatment

Giovanni Pompili, Silvia Tresoldi, Alessandra Primolevo, Loredana De Pasquale, Giovanni Di Leo, Gianpaolo Cornalba

Research output: Contribution to journalArticlepeer-review

Abstract

This study was conducted to evaluate whether ultrasound characteristics of thyroid nodules with a known cytologic diagnosis of "follicular pattern" (indicative of follicular hyperplasia, follicular adenoma or follicular carcinoma) can be used to define a nodule malignancy score to limit surgery to selected, higher-risk cases. In pre-operative ultrasound results of patients diagnosed with a "follicular pattern" on cytology who subsequently underwent surgery, each nodule feature was given a score from 0 (most likely benign) to 2 (most likely malignant), resulting in a total score ranging from 0 to 11. The total nodule score (total malignancy score) was then compared with the definitive histologic diagnosis. According to our results, surgery is advisable in patients with score≥4(79% of carcinomas), ultrasound follow-up seems to be appropriate for patients with a score of 3 (21% of carcinomas) and no action is recommended for patients with score

Original languageEnglish
Pages (from-to)1350-1355
Number of pages6
JournalUltrasound in Medicine and Biology
Volume39
Issue number8
DOIs
Publication statusPublished - Aug 2013

Keywords

  • Cytodiagnosis
  • Diagnostic imaging
  • Fine-needle biopsy
  • Follicular thyroid carcinoma
  • Thyroid nodule
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Biophysics

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