Managing for the long-term - Strategies for initiating and maintaining successful continuous dopaminergic stimulation treatment

Tove Henriksen, Per Odin, Jens Volkmann, Angelo Antonini

Research output: Contribution to journalArticle

Abstract

There are many factors that may influence treatment choice in patients with Parkinson's disease. While 'inclusion' criteria include the clinical need for short- and long-term improvement, there are some well defined contraindications to continuous dopaminergic stimulation (CDS) therapies, such as age, cognitive impairment, psychosis or severe orthostatic hypotension. These contraindications vary between CDS therapies and can help guide the choice of treatment. Patient preferences and the practicalities of the treatment modality also play an important part in the decision-making process. Treatment selection algorithms have been developed and presented, but they require refining and need to be expanded to include guidance on management decisions - for example, when initial CDS therapy fails. While more trial data are gathered and as management algorithms evolve, case studies continue to provide important information on practical aspects of CDS therapies.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalEuropean Neurological Review
Volume7
Issue numberSUPPL.1
Publication statusPublished - 2012

Keywords

  • Continuous dopaminergic stimulation
  • Deep brain stimulation
  • Levodopa/carbidopa intestinal gel infusion
  • Parkinson's disease
  • Subcutaneous apomorphine infusion
  • Treatment selection algorithm

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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