Abstract
Dendritic cells (DCs) induce and regulate T-cell responses, and tolerogenic DCs can promote the development of regulatory T cells with suppressive activity. The possibility of manipulating DCs using different pharmacological or biological agents, enabling them to exert tolerogenic activities, could be exploited to better control a variety of chronic inflammatory conditions, from autoimmune diseases to allograft rejection.
Original language | English |
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Pages (from-to) | 1033-1039 |
Number of pages | 7 |
Journal | Microbes and Infection |
Volume | 7 |
Issue number | 7-8 |
DOIs | |
Publication status | Published - Jun 2005 |
Keywords
- Allograft rejection
- Anti-inflammatory drugs
- Autoimmune diseases
- Calcitriol
- Immunomodulation
- Immunosuppressive agents
- Tolerogenic dendritic cells
- VDR agonist
- Vitamin D receptor
ASJC Scopus subject areas
- Microbiology
- Infectious Diseases