Mannose-binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients

R. Schreiber, A. V. Campos-Coelho, L. Brandão, R. L. Guimarães, A. J. Kamada, M. C. Ferreira-Sae, J. R. Matos-Souza, J. A. Cipolli, J. L. De Lima-Filho, S. Crovella, W. Nadruz

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Abstract

We investigated the possible role of Mannose binding lectin 2 (MBL2) functional polymorphisms in the prevalence of hypertension and hypertensive end-organ damage in 300 hypertensive patients and 313 normotensive individuals from Southern Brazil. Hypertensive subjects with MBL2 AO/OO genotypes presented lower C-reactive protein levels than AA individuals and consequently lower inflammatory status.

Original languageEnglish
Pages (from-to)525-527
Number of pages3
JournalInternational Journal of Immunogenetics
Volume38
Issue number6
DOIs
Publication statusPublished - Dec 2011

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ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Immunology
  • Genetics(clinical)

Cite this

Schreiber, R., Campos-Coelho, A. V., Brandão, L., Guimarães, R. L., Kamada, A. J., Ferreira-Sae, M. C., Matos-Souza, J. R., Cipolli, J. A., De Lima-Filho, J. L., Crovella, S., & Nadruz, W. (2011). Mannose-binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients. International Journal of Immunogenetics, 38(6), 525-527. https://doi.org/10.1111/j.1744-313X.2011.01036.x