Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome

Fernando Gianfrancesco, Teresa Esposito, Loretta Ruini, Remi Houlgatte, Ramaiah Nagaraja, Maurizio D'Esposito, Mariano Rocchi, Charles Auffray, David Schlessinger, Michele D'Urso, Antonino Forabosco

Research output: Contribution to journalArticle

Abstract

The positioning of Expressed Sequence Tags (ESTs) constitutes an important step towards a functional map of the human genome, including candidate genes for human genetic disorders that have been localized by linkage analysis. We localized 59 ESTs on the human X chromosome, including 44 derived from infant brain and 15 from adult muscle cDNA libraries. Localizations by a somatic cell hybrid panel were refined for five cDNAs by mapping them in yeast artificial chromosome (YAC) contigs.

Original languageEnglish
Pages (from-to)179-184
Number of pages6
JournalGene
Volume187
Issue number2
DOIs
Publication statusPublished - Mar 18 1997

Keywords

  • Human genome
  • Somatic cell hybrid
  • X physical and genetic map
  • X-linked disease

ASJC Scopus subject areas

  • Genetics

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  • Cite this

    Gianfrancesco, F., Esposito, T., Ruini, L., Houlgatte, R., Nagaraja, R., D'Esposito, M., Rocchi, M., Auffray, C., Schlessinger, D., D'Urso, M., & Forabosco, A. (1997). Mapping of 59 EST gene markers in 31 intervals spanning the human X chromosome. Gene, 187(2), 179-184. https://doi.org/10.1016/S0378-1119(96)00743-3