Mapping of gene encoding mouse placental alkaline phosphatase to chromosome 4

Mineko Terao, Dimitrina Pravtcheva, Frank H. Ruddle, Beatrice Mintz

Research output: Contribution to journalArticlepeer-review

Abstract

The gene encoding the mouse placental alkaline phosphatase (ALP; orthophosphoric-monoester phosphohydrolase, alkaline optimum, EC 3.1.3.1) is mapped to chromosome 4, based on Southern blot hybridization of the mouse cDNA with DNAs from mouse-Chinese hamster somatic cell hybrids. This assignment is consistent with the genetic analysis of the Akp-2 locus, which is responsible for the genetic variation of alkaline phosphatase enzyme in placenta as well as in liver, kidney, and bone.

Original languageEnglish
Pages (from-to)211-215
Number of pages5
JournalSomatic Cell and Molecular Genetics
Volume14
Issue number2
DOIs
Publication statusPublished - Mar 1988

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

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