Abstract
The recently isolated human WHN gene has been previously assigned to chromosome 17q11-12 using radiation hybrids. In this study, we constructed a YAC contig covering 17q11.2 between crystallinBA1 and neurofibromatosis 1 genes. By ordering known and novel markers, we determined the position of the WHN gene, and of the closely linked retinal 4 and sodium/dicarboxylate cotransporter genes. We also identified a new mononucleotide polymorphism contained within the untranslated exon 1 of the WHN gene, which may be useful for linkage and LOH studies.
Original language | English |
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Pages (from-to) | 199-202 |
Number of pages | 4 |
Journal | Molecular and Cellular Probes |
Volume | 13 |
Issue number | 3 |
DOIs | |
Publication status | Published - Jun 1999 |
Keywords
- Human WHN gene
- Retinal 4 gene
- Sodium/dicarboxylate cotransporter gene
- STR
- YAC contig
ASJC Scopus subject areas
- Cell Biology
- Molecular Biology