Mapping of human WHN gene in a 17q11.2 YAC contig and identification of an intragenic STR

L. Corrado, P. Colapietro, L. Larizza, P. Riva

Research output: Contribution to journalArticlepeer-review

Abstract

The recently isolated human WHN gene has been previously assigned to chromosome 17q11-12 using radiation hybrids. In this study, we constructed a YAC contig covering 17q11.2 between crystallinBA1 and neurofibromatosis 1 genes. By ordering known and novel markers, we determined the position of the WHN gene, and of the closely linked retinal 4 and sodium/dicarboxylate cotransporter genes. We also identified a new mononucleotide polymorphism contained within the untranslated exon 1 of the WHN gene, which may be useful for linkage and LOH studies.

Original languageEnglish
Pages (from-to)199-202
Number of pages4
JournalMolecular and Cellular Probes
Volume13
Issue number3
DOIs
Publication statusPublished - Jun 1999

Keywords

  • Human WHN gene
  • Retinal 4 gene
  • Sodium/dicarboxylate cotransporter gene
  • STR
  • YAC contig

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

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